Concentration Container Segmented Swirling Flow Avoidance Region
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Solution Overview
Problem
Existing concentration methods, such as those described in Patent Document 1, are inadequate for achieving accurate quantitative concentration of solutions, particularly for target molecules like proteins that thermally denature, as they do not effectively prevent the solution from being affected by swirling flows during the concentration process.
Innovation Solution
A container for concentration equipped with a supplying region for swirling gas and an avoidance region below it, where the swirling flow is minimized, allowing for the accumulation of the solution in a narrow tube with a smaller diameter, enabling precise quantitative concentration by preventing the solution inside the narrow tube from being affected by the swirling flow.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Productivity
If a swirling flow of gas is supplied to the solution to promote concentration, then the concentration efficiency is improved, but the solution cannot be accurately quantitatively concentrated due to continuous swirling effects
Solution Approach 1:
The container is divided into two distinct regions: a supplying region where swirling gas flow is introduced to promote concentration, and an avoidance region where the swirling flow is minimized or avoided. This spatial segmentation allows the solution to be concentrated efficiently in the supplying region while maintaining a stable, swirl-free zone in the avoidance region for accurate quantitative measurement.
Solution Approach 2:
Different regions of the container are given different functional qualities: the supplying region is designed to receive and utilize swirling gas flow for concentration promotion, while the avoidance region is designed to be free from swirling effects. This local differentiation of functional qualities enables both high concentration efficiency and accurate quantitative measurement within the same system.
2Productivity
If the solution is concentrated in a wide container to allow gas flow, then the concentration process is efficient, but visual observation of the liquid surface becomes difficult
Solution Approach 1:
The container structure is segmented into a wider supplying region that accommodates gas flow for efficient concentration, and a narrower avoidance region (narrow tube) where the solution accumulates after concentration. This segmentation allows the solution to be concentrated efficiently in the wide region while final observation occurs in the narrow region where the liquid surface is easily visible.
Solution Approach 2:
The container transitions from a wide cross-sectional dimension in the supplying region to a narrow cross-sectional dimension in the avoidance region (narrow tube). This dimensional change allows efficient gas-liquid interaction in the wide region while providing a narrow, easily observable liquid column in the avoidance region for accurate visual measurement of concentration.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
This configuration allows for accurate and stable concentration of solutions, enabling easy visual observation of the liquid surface and precise determination of the concentration level, facilitating quantitative concentration with enhanced accuracy and ease of use.
Implementation Method 1
a common concentration method is evaporative concentration by boiling. However, this method cannot be applied to target molecules that thermally denature, such as proteins. Meanwhile, Patent Document 1 proposes a method of promoting concentration of a solution by increase in specific interfacial area between the solution and a gas contacting the solution, the increase being obtained by applying a negative pressure to the gas to induce a spiral swirling flow of the gas and thereby form a swirling flow of the liquid.
Data Source
AI summary
A container for concentration includes a supplying region in which a swirling flow of a gas is supplied to a solution in the container for concentration, and an avoidance region that is situated below the supplying region and in which supplying of the swirling flow to the solution is avoided.