Integrated Condenser with Wettability Gradient for Breath Sampling

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Solution Overview

Problem

Existing breath-sampling techniques for exhaled human and animal breath are power hungry, bulky, and prone to variability in performance, with high risks of contamination and handling errors due to manual processing.

Innovation Solution

An integrated condenser with a micro-patterned sampler surface featuring a wettability gradient and a hydrophobic coating, which facilitates drop-wise condensation and passive aggregation of droplets towards a central collection point, reducing the need for manual processing and minimizing contamination risks.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If manual processing is used for breath samples, then flexibility in handling is maintained, but contamination risk and handling errors increase

Engineering Contradiction:
Improvereproducibility and reliabilityVSAvoidcontamination and handling errors
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent combines multiple functions (condensation, droplet aggregation, and sample collection) into a single integrated condenser device. The sampler surface integrates both the condensation function and the droplet aggregation function, eliminating the need for separate manual processing steps and reducing contamination risks.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The device performs automatic droplet aggregation through the wettability gradient on the sampler surface, which passively directs condensed droplets toward the center without requiring manual intervention. This self-service mechanism reduces handling errors and improves reliability.

Inventive Principle:
Principle #25Self-service

2Quantity of substance

If conventional breath sampling devices are used, then sample collection is achieved, but the devices are power hungry and bulky

Engineering Contradiction:
Improvebreath sample collectionVSAvoidpower consumption
Core Design Contradiction:
Quantity of substanceVSUse of energy by moving object

Solution Approach 1:

The wettability gradient on the sampler surface creates a passive droplet aggregation mechanism that does not require external power sources. Condensed droplets automatically move toward the center due to the surface energy difference, enabling power-free operation while maintaining effective sample collection.

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The patent replaces active mechanical or electrical pumping systems with a passive surface energy-driven mechanism. The wettability gradient substitutes for powered droplet transport systems, significantly reducing power consumption while maintaining sample collection effectiveness.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

3Quantity of substance

If conventional breath sampling devices are used, then sample collection is achieved, but the devices are bulky

Engineering Contradiction:
Improvebreath sample collectionVSAvoiddevice size
Core Design Contradiction:
Quantity of substanceVSVolume of moving object

Solution Approach 1:

The patent combines multiple functions (condensation, droplet aggregation, and sample collection) into a single integrated condenser device. The sampler surface integrates both the condensation function and the droplet aggregation function, eliminating the need for separate components and reducing overall device volume.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The passive wettability gradient mechanism replaces bulky active pumping and transport systems. By using surface energy differences to drive droplet aggregation, the device eliminates the need for large mechanical components, enabling miniaturization while maintaining sample collection capability.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

4Productivity

If drop-wise condensation is maintained for efficient heat transfer, then condensation efficiency is improved, but droplet aggregation becomes more difficult

Engineering Contradiction:
Improvecondensation efficiencyVSAvoiddroplet aggregation
Core Design Contradiction:
ProductivityVSEase of operation

Solution Approach 1:

The sampler surface has spatially varying wettability properties: the outer region maintains high hydrophobicity to promote drop-wise condensation and efficient heat transfer, while the inner region has lower hydrophobicity to facilitate droplet aggregation and movement toward the center. This local quality variation resolves the contradiction between maintaining condensation efficiency and enabling droplet aggregation.

Inventive Principle:
Principle #3Local quality

Solution Approach 2:

The patent changes the wettability parameter (hydrophobicity) across the sampler surface to create a gradient. By varying this surface property from the outer to inner region, the device maintains favorable conditions for both drop-wise condensation (outer region) and droplet aggregation (inner region), resolving the contradiction between these two functions.

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The integrated condenser enables portable, energy-efficient, and reliable breath sampling with high reproducibility and reliability, eliminating the need for manual processing and reducing contamination risks, while maintaining effective drop-wise condensation for efficient heat transfer.

Implementation Method 1

facilitates condensing at least a component in the received gas-phase sample into liquid-phase droplets

Methodology Applied
Scientific EffectCondensation: Condensation

Implementation Method 2

a hydrophobic coating disposed on the outer surface region (and/or the inner surface region) to facilitate drop-wise condensation

Methodology Applied
Scientific EffectHydrophobic effect: Hydrophobe

Implementation Method 3

the sampler surface may be increasingly less hydrophobic along a radial direction toward the center of the sampler surface, thereby creating an axisymmetric wettability gradient

Methodology Applied
Scientific EffectCapillary action: Capillary Action

Data Source

PatentUS10111606B2Integrated condenser for collecting droplets
Publication Date: 2018.10.30 RGT UNIV OF CALIFORNIA
  • US10111606B2 patent drawing
  • US10111606B2 patent drawing
  • US10111606B2 patent drawing

AI summary

An integrated condenser is described. This integrated condenser includes an outer surface region on a sampler surface that facilitates condensing at least a component in a received gas-phase sample into liquid-phase droplets on the sampler surface, and aggregating and moving the condensed droplets radially toward an inner surface region on the sampler surface that receives the condensed droplets. For example, the outer surface region may include a set of micro-patterned concentric rings, each of which includes a set of radially oriented wall-groove pairs. Moreover, the sampler surface may be increasingly less hydrophobic along a radial direction toward the center of the sampler surface, thereby creating an axisymmetric wettability gradient.