Conduction Velocity Mapping Using Unprojected Electrogram Data
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Solution Overview
Problem
Current methods for analyzing cardiac electrophysiology face challenges in accurately mapping conduction velocity due to errors introduced during data transformation, spatial localization, and interpolation, which can lead to inaccurate identification of arrhythmia initiation and maintenance sites.
Innovation Solution
The use of a multipolar catheter to calculate conduction velocity from unprojected, uninterpolated data in a single acquisition period, minimizing sources of error and improving data accuracy by triangulating conduction velocity from multiple data points simultaneously.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Measurement precision
If traditional methods using projected and interpolated data are used to map conduction velocity, then the mapping process is more complex and allows for broader data coverage, but errors are introduced during data transformation, spatial localization, and interpolation that reduce measurement precision
Solution Approach 1:
The patent extracts and eliminates the error-prone intermediate steps of data projection and interpolation by directly calculating conduction velocity from raw, unprocessed electrogram data. This removes the transformation layer that introduces errors, achieving higher measurement precision without requiring complex error correction mechanisms.
Solution Approach 2:
Instead of the traditional approach of first creating a projected and interpolated activation map and then calculating conduction velocity from it, the patent inverts the process by directly computing conduction velocity from the original unprocessed data, thereby avoiding the accumulation of transformation errors.
2Productivity
If multiple data acquisitions are used to improve data coverage, then more comprehensive arrhythmia analysis is possible, but the time required for analysis increases and real-time capability is reduced
Solution Approach 1:
The patent achieves sufficient data coverage for accurate conduction velocity calculation by using data from a single acquisition period, which is less than what traditional methods require. This partial action approach maintains real-time capability while providing adequate information for clinical decision-making.
Solution Approach 2:
The system performs conduction velocity calculation immediately from the first available acquisition of electrogram data, without waiting for multiple acquisitions or extensive data accumulation. This preliminary action enables real-time arrhythmia analysis and faster clinical intervention.
3Reliability
If unipolar electrograms are used for mapping, then broader electrical activity coverage is achieved, but the signals contain more noise and far-field interference that reduces signal quality
Solution Approach 1:
The patent combines information from multiple unipolar electrogram channels through simultaneous multi-point analysis to calculate conduction velocity. By merging data from multiple electrodes recording broader electrical activity, the system maintains comprehensive coverage while the direct calculation method filters out noise and far-field interference that would otherwise contaminate individual unipolar signals.
Data Source
AI summary
Systems and methods for quantifying cardiac electrophysiologic signals. An electronic processor receives a unipolar electrogram signal from each of a plurality of electrodes positioned at different locations of a heart. The electronic processor then calculates or measures a bipolar electrogram signal based on a difference between the unipolar electrogram signal for a first electrode and the unipolar electrogram signal for a second electrode. A local activation time (LAT) difference between a location of the first electrode and a local of the second electrode is then determined based on a voltage amplitude of the bipolar electrogram signal. The LAT difference is indicative of an amount of time between a local activation of a propagating wavefront at the location of the first electrode and a local activation of the propagating wavefront at the location of the second electrode.