Cone-Shaped Sample Injection Channel for Particle Detection
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Solution Overview
Problem
Current particle detection devices face difficulties in efficiently exporting or absorbing sample liquid from the detection pool due to its depth and inner diameter, leading to challenges in mixing markers with the sample liquid for accurate detection.
Innovation Solution
A particle detection device with a substrate and detection units, including a sample injection part that cooperates with a liquid driving device to seal and facilitate the entry and exit of sample liquid from the detection pool, utilizing a cone-shaped sample injection channel and elastomer sealing parts to ensure effective sealing and mixing of markers with the sample liquid.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Quantity of substance
If the detection pool has a certain depth and inner diameter to accommodate sufficient sample liquid, then the sample liquid volume is sufficient for detection, but the sample liquid cannot be efficiently exported or absorbed from the detection pool
Solution Approach 1:
The patent applies a cone-shaped sample injection channel with varying inner diameter, where the inner diameter is larger at the detection pool end and smaller at the injection port end. This dynamic geometric design allows the channel to adapt to different flow requirements: the larger diameter near the detection pool facilitates efficient liquid export, while the smaller diameter at the port enables effective absorption, thereby resolving the contradiction between accommodating sufficient sample volume and achieving efficient liquid handling.
2Ease of manufacture
If the sample injection channel has a uniform inner diameter, then the manufacturing is simpler, but the mixing of markers with sample liquid is insufficient
Solution Approach 1:
The patent implements local quality variation in the sample injection channel by designing it with a cone shape where the inner diameter changes along the flow direction. The channel has a larger inner diameter near the detection pool and a smaller inner diameter near the injection port, creating different flow characteristics in different sections. This local geometric variation enhances marker mixing efficiency while maintaining manufacturing feasibility through standard conical machining or molding processes.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
Enables quick and repeated import and export of sample liquid from the detection pool, ensuring efficient mixing of markers, thereby improving detection accuracy and efficiency in clinical testing, drug analysis, and environmental monitoring.
Implementation Method 1
the sample injection part further includes an elastomer sealing part, wherein the elastomer sealing part is provided with a through hole, and the elastomer sealing part is installed on the sample injection channel and/or the sample injection port
Implementation Method 2
an inner diameter of the sample injection channel gradually decreases along a direction from the sample injection port to the detection pool
Data Source
AI summary
A particle detection device is provided. The particle detection device may include a substrate and at least one detection unit setting on the substrate. The at least one detection unit may include: a detection pool, configured to accommodate a sample liquid; a sample injection part communicating the detection pool, the sample injection part being sealable with a liquid driving device, wherein the liquid driving device and the sample injection part cooperate to enable the sample liquid to get in and out of the detection pool