Configurable Biopharmaceutical Device for High-Pressure Connections

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Solution Overview

Problem

Existing biopharmaceutical device arrangements face challenges in flexibility, error susceptibility during connection, pressure resistance, and drainability, particularly when handling complex hose connections and specific process volumes.

Innovation Solution

A configurable device with a solid body featuring predefined pipe sections and plug-in locations, allowing for customizable functional elements that ensure pressure stability, flexibility, and improved drainability, enabling high-pressure operations and adaptable configurations for various process requirements.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of operation

If conventional hose lines are used for connections, then flexibility and ease of installation are improved, but pressure resistance and system reliability deteriorate

Engineering Contradiction:
Improveease of installationVSAvoidpressure resistance
Core Design Contradiction:
Ease of operationVSReliability

Solution Approach 1:

The patent merges the connection functions and piping structures into a single integrated solid body. The body contains multiple pipe sections and connection locations formed directly within the molded structure, eliminating the need for separate hose lines and connectors. This integration maintains ease of installation through modular design while significantly improving pressure resistance by using a rigid, monolithic structure that can withstand high pressures without the weaknesses of conventional hose connections.

Inventive Principle:
Principle #5Merging (Combining)

2Adaptability or versatility

If complex hose connections are used to achieve versatile configurations, then adaptability is improved, but error susceptibility and operation complexity worsen

Engineering Contradiction:
Improveconfiguration flexibilityVSAvoidconnection complexity
Core Design Contradiction:
Adaptability or versatilityVSDevice complexity

Solution Approach 1:

The solid body is designed with multiple connection locations and pipe sections that can be configured for different unit operations. The same basic body structure serves multiple functions through selective connection of process components at various locations. This universal design provides adaptability for different applications while simplifying operations, as the modular connection system reduces complexity compared to custom hose arrangements for each configuration.

Inventive Principle:
Principle #6Universality (Multi-functionality)

3Ease of manufacture

If conventional process setups are used, then ease of manufacture is improved, but pressure stability and system safety worsen

Engineering Contradiction:
Improvemanufacturing simplicityVSAvoidpressure stability
Core Design Contradiction:
Ease of manufactureVSStress or pressure

Solution Approach 1:

The device is designed as a disposable single-use system manufactured using injection molding techniques. This approach maintains ease of manufacture through efficient plastic molding processes while achieving superior pressure stability. The solid body structure, molded as a single piece or pre-assembled module, provides inherent pressure resistance and system safety that conventional assembled hose systems cannot match, while remaining cost-effective for single-use applications.

Inventive Principle:
Principle #27Cheap short-living objects (Disposable)

4Manufacturing precision

If standardized device arrangements are used for specific process steps, then manufacturing precision is improved, but adaptability and versatility worsen

Engineering Contradiction:
Improvedevice standardizationVSAvoidprocess flexibility
Core Design Contradiction:
Manufacturing precisionVSAdaptability or versatility

Solution Approach 1:

The device employs a segmented modular architecture where the solid body is divided into distinct functional sections with standardized connection points. Each module can be manufactured with high precision using standardized molding tools, ensuring manufacturing consistency. Meanwhile, the modular segments can be selectively connected and configured for different process steps, providing adaptability and versatility without sacrificing manufacturing precision.

Inventive Principle:
Principle #1Segmentation

Data Source

PatentUS11998920B2Configurable device for the flexible provision of connections and/or functions in a biopharmaceutical process
Publication Date: 2024.06.04 SARTORIUS STEDIM BIOTECH GMBH
  • US11998920B2 patent drawing
  • US11998920B2 patent drawing
  • US11998920B2 patent drawing

AI summary

A configurable device for the flexible provision of connections and/or functions in a biopharmaceutical process includes a body in which predefined pipe sections and plug-in locations are formed by recesses in the material of the body. The configurable device further includes a plurality of functional elements which are adapted to be inserted into the plug-in locations.