Conformable Cyanoacrylate Elastomer Coating for Skin

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Solution Overview

Problem

Conventional skin barrier products, including occlusive pastes and cyanoacrylate-based coatings, are messy, interfere with ostomy device securement, and are brittle, lacking flexibility and durability on moist skin surfaces.

Innovation Solution

A conformable coating composition combining a polymerizable cyanoacrylate monomer, an elastomer, and a volatile liquid, which forms a durable, flexible film that inhibits skin surface adhesion and provides hemostatic properties without being brittle, using alpha-cyanoacrylates and siliconized rubber with high elastomer content and specific volatile solvents.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Strength

If cyanoacrylate-based coatings are used to form a durable barrier film on skin, then the coating provides strong adhesion and durability, but the coating becomes brittle and lacks flexibility on skin surfaces

Engineering Contradiction:
Improvecoating adhesion and durabilityVSAvoidcoating flexibility
Core Design Contradiction:
StrengthVSAdaptability or versatility

Solution Approach 1:

The patent combines cyanoacrylate polymer with elastomer particles to create a composite coating material. The cyanoacrylate provides strong adhesion and durability, while the elastomer particles dispersed throughout the matrix provide flexibility and conformability to skin surfaces. This composite structure resolves the contradiction by integrating two materials with complementary properties.

Inventive Principle:
Principle #40Composite materials

2Productivity

If cyanoacrylate monomer is used quickly to form a film over skin, then the coating forms rapidly even over moist skin, but there is a risk of adhering two skin surfaces together

Engineering Contradiction:
Improvecoating formation speedVSAvoidskin surface adhesion
Core Design Contradiction:
ProductivityVSObject-affected harmful factors

Solution Approach 1:

The coating composition is designed with different components serving localized functions: the cyanoacrylate monomer provides rapid film formation, while the elastomer particles and volatile liquid specifically address the adhesion problem at skin surfaces. The elastomer particles create a non-tacky surface layer that prevents skin surface adhesion while maintaining rapid overall coating formation.

Inventive Principle:
Principle #3Local quality

Solution Approach 2:

The elastomer particles act as an intermediary between the cyanoacrylate polymer matrix and the skin surface. They modify the surface properties of the coating to prevent excessive adhesion between skin surfaces while allowing the cyanoacrylate to maintain its rapid film-forming capability. The volatile liquid also serves as an intermediary to control surface tackiness during the drying process.

Inventive Principle:
Principle #24Intermediary (Mediator)

3Reliability

If conventional occlusive barrier pastes are used to protect skin, then the skin is protected from moisture and enzymes, but the products are messy to apply and clean up and interfere with ostomy device securement

Engineering Contradiction:
Improveskin protectionVSAvoidapplication and cleanup convenience
Core Design Contradiction:
ReliabilityVSEase of operation

Solution Approach 1:

The coating utilizes phase transition from liquid to solid film through solvent evaporation. The composition is applied as a liquid that quickly forms a solid protective film as the volatile liquid evaporates. This provides the reliability of a protective barrier with the ease of operation of a liquid application, eliminating the messiness of traditional pastes and allowing easy donning of ostomy devices.

Inventive Principle:
Principle #36Phase transitions

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The coating provides a flexible, durable, and non-stinging barrier that maintains adhesion to skin while preventing adhesion between skin surfaces, with enhanced elongation capabilities and reduced tackiness, suitable for protecting and treating various skin and mucous membrane injuries.

Implementation Method 1

a conformable coating composition that comprises a polymerizable cyanoacrylate monomer, an elastomer, and a volatile liquid

Methodology Applied
Scientific EffectEvaporation: Evaporation

Implementation Method 2

a polymerizable cyanoacrylate monomer... A coating formed from the conformable coating composition comprises a polymerized cyanoacrylate

Methodology Applied
Scientific EffectPolymerization: Photopolymerisation

Data Source

PatentUS9301928B2Conformable coating and composition
Publication Date: 2016.04.05 SOLVENTUM INTELLECTUAL PROPERTIES CO

AI summary

The disclosed conformable coating provides a highly durable and resilient film useful for protecting and repairing surfaces such as skin and mucous membranes. The coating comprises 0.1% to 65% wt. of a polymerized cyanoacrylate monomer and at least 35% wt. of an elastomer phase. The conformable coating composition comprises a polymerizable cyanoacrylate monomer, an elastomer, and a volatile liquid. The cyanoacrylate monomer is 0.1 to 65% wt. of the nonvolatile portion, the elastomer in an elastomer phase is at least 35% wt. of the nonvolatile portion, and the volatile liquid is at least 40% wt. of the total composition.