Conical Balloon Catheter for Subintimal Re-entry

Resolve Bottlenecks,
Find Innovative Solutions
Generate Solutions

Solution Overview

Problem

Chronic total occlusions (CTOs) in blood vessels pose challenges for recanalization, as it is difficult or impossible to pass through the occlusion with medical devices in an antegrade direction, and re-entering the true lumen from the subintimal space can be problematic.

Innovation Solution

A balloon catheter with a conical inflatable balloon, secured to a catheter shaft, is advanced into a subintimal space distal to the occlusion, inflated to orient the guidewire lumen towards the true lumen, allowing a penetration member to re-enter the vessel lumen, facilitating recanalization.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of operation

If a conventional catheter is used to navigate the subintimal space, then the catheter can be advanced around the occlusion, but the guidewire lumen cannot be properly oriented towards the true lumen for re-entry

Engineering Contradiction:
Improveorientation of guidewire lumenVSAvoidcatheter structure
Core Design Contradiction:
Ease of operationVSDevice complexity

Solution Approach 1:

The balloon is designed with a conical shape that allows it to dynamically orient the guidewire lumen towards the true lumen when inflated in the subintimal space. The conical geometry creates an automatic directional alignment function that simplifies the re-entry maneuver without requiring complex active control mechanisms

Inventive Principle:
Principle #15Dynamics

Solution Approach 2:

The conical balloon shape with its curved surface provides the necessary geometry to deflect and orient the guidewire lumen towards the true lumen. The curved conical surface naturally guides the penetration member in the desired direction, eliminating the need for complex angular adjustment mechanisms

Inventive Principle:
Principle #14Spheroidality (Curvature)

2Productivity

If a penetration member is advanced to re-enter the true lumen from the subintimal space, then recanalization can be achieved, but the procedure becomes difficult and time-consuming

Engineering Contradiction:
Improverecanalization efficiencyVSAvoidre-entry difficulty
Core Design Contradiction:
ProductivityVSEase of operation

Solution Approach 1:

The catheter is pre-positioned in the subintimal space with the conical balloon ready for inflation. The balloon is inflated in advance to create the oriented guidewire lumen configuration before the penetration member is advanced, thereby simplifying the re-entry action and reducing procedural time

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The conical balloon acts as an intermediary device that facilitates the transition from subintimal space to true lumen. By inflating the balloon, the guidewire lumen is oriented towards the true lumen, making the penetration and re-entry process more efficient and less difficult

Inventive Principle:
Principle #24Intermediary (Mediator)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The balloon catheter effectively navigates the subintimal space to re-enter the true lumen of the blood vessel, enabling recanalization of occluded vessels by deflecting the guidewire lumen towards the vessel lumen, thus overcoming the difficulties of CTOs.

Implementation Method 1

an inflatable balloon having a proximal waist secured to the catheter shaft and a distal waist secured to the catheter shaft

Methodology Applied
Scientific EffectInflation: Pressure Increase

Data Source

PatentEP3270999B1Subintimal re-entry balloon catheter and method of forming thereof
Publication Date: 2022.12.07 BOSTON SCIENTIFIC SCIMED INC
  • EP3270999B1 patent drawingFigure 1
  • EP3270999B1 patent drawingFigure 2
  • EP3270999B1 patent drawingFigure 3

AI summary

A balloon catheter 10 including a catheter shaft 12 and an inflatable balloon 20 secured to a distal end region of the catheter shaft. The inflatable balloon has a generally conical shape in a fully inflated configuration having a proximal conical portion 42 that tapers away from the central longitudinal axis in a distal direction from a proximal waist of the balloon and a distal conical portion 46 that tapers toward the central longitudinal axis in a distal direction toward a distal waist of the balloon, with a radially outermost extent 44 of the balloon located between the proximal conical portion and the distal conical portion. The proximal conical portion, the distal conical portion and/ or the radially outermost extent of the balloon has an elliptical cross- section taken in a plane perpendicular to the central longitudinal axis of the catheter shaft.