Conical Membrane Micro Pump Valve for Precise Pulsatile Dosing

Resolve Bottlenecks,
Find Innovative Solutions
Generate Solutions

Solution Overview

Problem

Current micro-pumps for insulin delivery face challenges in achieving precise flow rate accuracy, avoiding air bubbles, and maintaining efficient operation with particulate materials, while also requiring cost-effective manufacturing and assembly processes to support periodic use.

Innovation Solution

A pulsatile micro-pump design featuring a conical shaped valve seat and a membrane with a hole, allowing fluid flow when pressure differences exceed a certain threshold, combined with elastomeric materials for effective sealing and reduced membrane flexing, which enhances flow rate and prevents reverse fluid flow.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If a membrane valve is used to control fluid flow in the micro-pump, then flow direction control is improved, but membrane flexing increases causing volume variation and reduced delivery precision

Engineering Contradiction:
Improveflow direction controlVSAvoidfluid delivery precision
Core Design Contradiction:
ReliabilityVSManufacturing precision

Solution Approach 1:

The patent applies curvature by designing the membrane with a pre-formed dome shape and the valve seat with a corresponding curved surface. This curvature distribution allows the membrane to flex uniformly during operation, reducing stress concentration and minimizing volume variation caused by excessive flexing, thereby maintaining delivery precision while enabling reliable flow direction control.

Inventive Principle:
Principle #14Spheroidality (Curvature)

Solution Approach 2:

The patent changes physical parameters of the membrane including its thickness, material composition, and pre-tensioning forces. By optimizing these parameters, the membrane achieves the right balance between flexibility (for flow control) and stiffness (for maintaining volume precision), resolving the contradiction between reliable flow direction control and manufacturing precision.

Inventive Principle:
Principle #35Parameter changes

2Reliability

If the membrane is made more flexible to improve sealing, then sealing effectiveness is improved, but volume variation increases reducing flow rate accuracy

Engineering Contradiction:
Improvesealing effectivenessVSAvoidflow rate accuracy
Core Design Contradiction:
ReliabilityVSManufacturing precision

Solution Approach 1:

The patent optimizes membrane parameters including thickness, material properties, and pre-tensioning to achieve the optimal balance between flexibility and stiffness. The membrane is made sufficiently flexible to ensure effective sealing against the valve seat, while maintaining adequate stiffness through controlled thickness and pre-tensioning to minimize volume variation and maintain flow rate accuracy within +/- 2.50 nl.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The curved dome shape of the membrane distributes flexing stresses more evenly during operation, allowing the membrane to be sufficiently flexible for sealing while reducing the impact of flexing on volume variation. This geometric optimization enables both good sealing and acceptable flow rate accuracy.

Inventive Principle:
Principle #14Spheroidality (Curvature)

3Manufacturing precision

If the pumping chamber volume is reduced to improve dosing precision, then dosing accuracy is improved, but the chamber becomes more susceptible to air bubble retention

Engineering Contradiction:
Improvedosing accuracyVSAvoidair bubble management
Core Design Contradiction:
Manufacturing precisionVSReliability

Solution Approach 1:

The patent designs the pumping chamber with curved surfaces and optimized geometry that facilitate air bubble removal. The chamber shape includes features that promote bubble coalescence and directed flow paths that guide bubbles toward the inlet, ensuring that even in a small volume chamber (50-500 nl), air bubbles are effectively managed without compromising dosing accuracy.

Inventive Principle:
Principle #14Spheroidality (Curvature)

4Weight of moving object

If conventional micro-pump designs are used, then portability is achieved, but flow rate accuracy varies by more than +/- 2.50 nl

Engineering Contradiction:
ImproveportabilityVSAvoidflow rate accuracy
Core Design Contradiction:
Weight of moving objectVSManufacturing precision

Solution Approach 1:

The patent employs curved membrane design and optimized chamber geometry to minimize dead volumes and improve fluid displacement efficiency. This enables miniaturized portable pumps to achieve flow rate accuracy within +/- 2.50 nl by reducing the impact of manufacturing tolerances and minimizing air entrapment, while maintaining the portability advantage of small size.

Inventive Principle:
Principle #14Spheroidality (Curvature)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The design achieves precise fluid delivery with reduced volume variation, effective sealing in the presence of particles, and cost-effective manufacturing, suitable for high-volume production and low-cost applications.

Implementation Method 1

When the pressure on the side of the membrane from which liquid is allowed to enter and pass through the micro valve, exceeds the pressure on the opposite side of the membrane, the membrane releases its seal on the valve seat and fluid leaks from one side of the membrane to the opposite side

Methodology Applied
Scientific EffectPressure difference: Pressure Gradient

Implementation Method 2

Passive, normally closed one way membrane micro valve designs are commonly employed in micro pump design... The construction of these micro valves typically comprises a membrane that serves to separate the fluid at the inlet to the pumping chamber from that present in the pumping chamber

Methodology Applied
Scientific EffectElastic sealing: Elasticity

Data Source

PatentEP3521669B1Pulsating micro pump comprising a one way valve
Publication Date: 2021.10.20 VICENTRA BV
  • EP3521669B1 patent drawingFigure 1
  • EP3521669B1 patent drawingFigure 2
  • EP3521669B1 patent drawingFigure 3

AI summary

An one way valve comprising: a conical shaped valve seat (1); and a membrane (2) having a hole (3) that is located around the conical valve seat, such that a surface (60) of the valve seat seals (1) onto an inner periphery (61) of the hole (3) in the membrane (2), wherein, in use, the membrane (2) is deflected from the surface (60) of the valve seat (1) to provide a fluid path across the membrane (2) and allowing fluid to flow from one side of the membrane (2) to the other.