Contact Lens Glucose Detection via Photonic Crystal Spectral Shift

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Solution Overview

Problem

Current methods for detecting glucose concentration in the human body are invasive, costly, and inefficient, with traditional blood drawing methods causing trauma and having low detection efficiency.

Innovation Solution

A contact lens integrated with a molecularly imprinted photonic crystal layer that senses glucose in tears, using a spectrum sensing device to determine glucose concentration and trigger warnings or insulin release as needed, allowing for non-invasive and real-time glucose monitoring.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If traditional blood drawing methods are used for glucose detection, then detection accuracy can be achieved, but it causes trauma and has low detection efficiency

Engineering Contradiction:
Improvedetection efficiencyVSAvoidtrauma
Core Design Contradiction:
ProductivityVSObject-affected harmful factors

Solution Approach 1:

The patent replaces the mechanical blood drawing system with an optical sensing system. The contact lens incorporates a photonic crystal array that interacts with glucose molecules in tears through optical interactions, detecting glucose concentration through spectral changes rather than mechanical blood extraction. This substitution eliminates trauma while maintaining detection capability.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The patent uses tears as an intermediary medium to detect blood glucose levels. Instead of directly measuring blood glucose through invasive means, the system measures glucose concentration in tears, which correlates with blood glucose levels. This intermediary approach enables non-invasive detection while providing accurate glucose monitoring data.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Reliability

If invasive glucose detection methods are used, then reliable glucose concentration data can be obtained, but the process is costly and inefficient

Engineering Contradiction:
Improveglucose concentration data reliabilityVSAvoiddetection system complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The contact lens serves multiple functions: it acts as both a corrective vision device and a glucose sensing platform. The photonic crystal array is integrated directly into the contact lens structure, allowing the same device to provide both optical correction and biochemical sensing, thereby reducing overall system complexity and cost.

Inventive Principle:
Principle #6Universality (Multi-functionality)

Solution Approach 2:

The patent utilizes spectral redshift changes in the photonic crystal array as glucose binds to the molecularly imprinted polymer. This optical signal change provides a simple, reliable, and cost-effective detection mechanism that does not require complex electronic sensors or processing systems, maintaining reliability while reducing device complexity.

Inventive Principle:
Principle #32Color changes

3Loss of time

If real-time glucose monitoring is implemented, then timely alerts can be provided, but the system complexity increases

Engineering Contradiction:
Improveresponse time for glucose alertsVSAvoidmonitoring system complexity
Core Design Contradiction:
Loss of timeVSDevice complexity

Solution Approach 1:

The contact lens system performs self-detection and self-sensing without requiring external complex instrumentation. The photonic crystal array directly interacts with glucose in tears and produces an optical signal that can be read by simple spectral sensors, enabling real-time monitoring with minimal system complexity. The system serves itself by using the natural optical properties of the photonic crystal to provide continuous glucose data.

Inventive Principle:
Principle #25Self-service

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Enables quick, non-invasive, and cost-effective glucose monitoring by detecting spectral redshift in the contact lens, correlating tear glucose levels to blood glucose levels, and providing timely alerts or regulatory responses to maintain healthy glucose ranges.

Implementation Method 1

obtain a spectral redshift value of the glucose detection sheet according to the signal, so as to determine the glucose concentration in the tears of the user

Methodology Applied
Scientific EffectSpectral redshift:

Implementation Method 2

a glucose recognition layer including a photonic crystal array provided therein

Methodology Applied
Scientific EffectPhotonic crystal: Photonic Crystal

Implementation Method 3

the glucose recognition layer is a molecularly imprinted photonic crystal layer

Methodology Applied
Scientific EffectMolecular imprinting:

Implementation Method 4

a glucose recognition layer including a photonic crystal array provided therein, and the glucose recognition layer being configured to recognize glucose

Methodology Applied
Scientific EffectAdsorption: Adsorption

Data Source

PatentUS11529098B2Contact lens, system and method for monitoring glucose
Publication Date: 2022.12.20 BEIJING BOE TECH DEV CO LTD
  • US11529098B2 patent drawing
  • US11529098B2 patent drawing
  • US11529098B2 patent drawing

AI summary

A contact lens includes a contact lens body and a glucose detection sheet disposed on the contact lens body. The glucose detection sheet includes a glucose recognition layer, a photonic crystal array is provided in the glucose recognition layer, and the glucose recognition layer is configured to recognize glucose.