Contact Lens Treatment Solution for Persistent Hydrophilicity
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Solution Overview
Problem
Existing contact lens treatment solutions are inadequate in providing persistent hydrophilicity to contact lens surfaces, which is necessary to prevent dirt adhesion and effectively remove adhered dirt.
Innovation Solution
A contact lens treatment solution containing specific copolymers A and B in a specific ratio, where copolymer A is derived from monomers (a) and (b) with a weight-average molecular weight of 400,000 to 700,000, and copolymer B from monomers (c) and (d) with a weight-average molecular weight of 20,000 to 90,000, used in a simple immersion process to remove dirt and impart persisting hydrophilicity.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Ease of manufacture
If a detergent containing surfactant, oxidizing agent and polishing agent is used to remove dirt from CL, then dirt removal effect is improved, but prevention of dirt adhesion is insufficient
Solution Approach 1:
The patent combines multiple functional components into a single treatment solution: phosphorylcholine group-containing polymer for hydrophilization and dirt prevention, alkylamide polyoxyethylene ether sulfate salt for surfactant action, and hydrolase enzyme for biological degradation. This merging allows simultaneous achievement of both dirt removal and prevention functions that were previously achieved by separate methods
Solution Approach 2:
The treatment solution is designed to perform multiple functions: the phosphorylcholine polymer provides hydrophilicity and prevents dirt adhesion, the surfactant component removes existing dirt through wetting and emulsification, and the hydrolase enzyme breaks down organic contaminants. This multi-functionality resolves the contradiction by providing both removal and prevention capabilities in one formulation
2Reliability
If phosphorylcholine group-containing polymer is used to hydrophilize CL surface, then prevention of dirt adhesion is improved, but removal of adhered dirt is insufficient
Solution Approach 1:
The patent merges the hydrophilization function (phosphorylcholine polymer) with dirt removal functions (surfactant and hydrolase) in a single treatment solution. This allows the solution to first prevent dirt adhesion through hydrophilicity while simultaneously removing any adhered dirt through the combined action of surfactant and enzyme, resolving the limitation of using phosphorylcholine alone
Solution Approach 2:
The treatment solution uses a composite formulation combining different molecular components: phosphorylcholine polymer for surface modification, alkylamide polyoxyethylene ether sulfate salt for surfactant action, and hydrolase enzyme for biological degradation. This composite approach enables both prevention and removal functions to work synergistically
3Ease of manufacture
If CL treatment solution contains specific components to remove dirt, then detergency is improved, but persistence of hydrophilicity is insufficient
Solution Approach 1:
The patent optimizes the concentration ratio of phosphorylcholine group-containing polymer to other components in the treatment solution. By controlling this parameter, the solution achieves effective dirt removal while ensuring sufficient hydrophilicity persistence on the CL surface. The specific ratio ensures that the hydrophilic polymer remains on the surface long-term while the surfactant and enzyme components effectively remove dirt
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The solution effectively removes adhered dirt and imparts persisting hydrophilicity to contact lens surfaces, enhancing wearability and preventing dirt adhesion, as demonstrated by improved detergency and hydrophilicity retention in examples.
Implementation Method 1
a copolymer obtained by copolymerization of a monomer (a) represented by the following formula (1) and a monomer (b) represented by the following formula (2)... a copolymer obtained by copolymerization of a monomer (c) represented by the following formula (3) and a monomer (d) represented by the following formula (4)
Implementation Method 2
can remove dirt having adhered to CL surfaces
Implementation Method 3
can impart persisting hydrophilicity to CL surfaces
Data Source
AI summary
The present invention is a contact lens treatment solution containing the following copolymer A and copolymer B in a ratio of A/B=1000/1 to 2/1 (by weight). According to the present invention, there can be provided a contact lens treatment solution capable of removing dirt having adhered to contact lens surfaces and capable of imparting persisting hydrophilicity to contact lens surfaces, by simple immersion treatment.Copolymer A: a copolymer obtained by copolymerization of a monomer (a) represented by formula (1) and a monomer (b) represented by formula (2), in which the copolymerization ratio of the monomer (a) to the monomer (b), a/b=7/3 to 9/1 (by mol), and having a weight-average molecular weight of 400,000 to 700,000.Copolymer B: a copolymer obtained by copolymerization of a monomer (c) represented by formula (3) and a monomer (d) represented by formula (4), in which the copolymerization ratio of the monomer (c) to the monomer (d), c/d=1/4 to 9/1 (by mol), and having a weight-average molecular weight of 20,000 to 90,000.