Continuous Tablet Production System with Real-Time Mixing Control

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Solution Overview

Problem

Conventional batch methods for producing tablets, such as pharmaceutical products, face challenges in continuous processing, requiring extensive material usage, high costs, and difficulty in timely monitoring of mixing degrees, leading to inconsistent product quality and inefficiencies in scaling up production.

Innovation Solution

A system that continuously monitors the mixing degree of powdery materials using sensors and adjusts the feed rate and mixing speed to maintain a predetermined mixing range, ensuring consistent quality and optimizing the production process by integrating measuring feeders and mixers with a control system to adjust the flow rate and rotational speed of the compression molding machine.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of manufacture

If batch method is used for tablet production, then each process can be conducted separately with individual facility design, but standby periods occur between processes and large space is required

Engineering Contradiction:
Improveindividual facility designVSAvoidstandby periods
Core Design Contradiction:
Ease of manufactureVSLoss of time

Solution Approach 1:

The patent implements continuous processing where granulating, drying, grading, mixing, and compression molding are conducted without standby periods between processes. Intermediate products are continuously fed from one process to the next, eliminating idle time and maintaining continuous operational flow throughout the production line.

Inventive Principle:
Principle #20Continuity of useful action

Solution Approach 2:

The patent combines multiple separate batch processes into a single integrated continuous production line. Facilities for granulating, drying, grading, mixing, and compression molding are merged into one continuous system where materials flow through all stages without interruption, reducing total space requirements while maintaining manufacturing flexibility.

Inventive Principle:
Principle #5Merging (Combining)

2Device complexity

If batch method is used for tablet production, then facility design can be simplified for each process, but occupation of large space is required

Engineering Contradiction:
Improvefacility designVSAvoidspace occupation
Core Design Contradiction:
Device complexityVSArea of stationary object

Solution Approach 1:

The patent combines multiple separate batch processes into a single integrated continuous production line. Facilities for granulating, drying, grading, mixing, and compression molding are merged into one continuous system where materials flow through all stages without interruption, reducing total space requirements while maintaining manufacturing flexibility.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The continuous production line is designed as a universal system that handles multiple operations (granulating, drying, grading, mixing, compression) in sequence within a single integrated facility, reducing the need for separate dedicated spaces for each process while maintaining the ability to optimize each stage.

Inventive Principle:
Principle #6Universality (Multi-functionality)

3Device complexity

If conventional mixing monitoring is used, then sensor configuration is simple, but mixing degree cannot be promptly monitored and corrective action is delayed

Engineering Contradiction:
Improvesensor configurationVSAvoidmixing degree monitoring
Core Design Contradiction:
Device complexityVSMeasurement precision

Solution Approach 1:

The patent incorporates sensors that continuously monitor the mixing degree of powdery materials in real-time during the mixing process. The measured mixing degree information is fed back to the control system, which automatically adjusts mixing parameters or feed rates to maintain the mixing degree within the predetermined range, enabling prompt detection and correction of mixing issues.

Inventive Principle:
Principle #23Feedback

Solution Approach 2:

The patent replaces conventional mechanical sampling and offline analysis methods with optical or electromagnetic sensors that non-invasively measure mixing degree in real-time. This substitution enables continuous monitoring without disrupting the production flow and provides immediate feedback for corrective action.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

4Quantity of substance

If batch production is used, then material usage for verification experiments is reduced, but production efficiency and timeliness are compromised

Engineering Contradiction:
Improveraw material usageVSAvoidproduction efficiency
Core Design Contradiction:
Quantity of substanceVSProductivity

Solution Approach 1:

The patent implements continuous processing where granulating, drying, grading, mixing, and compression molding are conducted without standby periods between processes. Intermediate products are continuously fed from one process to the next, eliminating idle time and maintaining continuous operational flow throughout the production line.

Inventive Principle:
Principle #20Continuity of useful action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This system enables continuous and efficient monitoring of mixing degrees, maintaining high product quality by correcting flow rates and segregation issues, thereby reducing material waste and operational costs while ensuring consistent production.

Implementation Method 1

The at least one measuring device comprises a unit for directing input radiation into said vessel, and at least one detector unit for detecting output radiation formed by interaction of said input radiation with said materials in said vessel.

Methodology Applied
Scientific EffectRadiation interaction: Absorption Spectroscopy

Data Source

PatentEP3225387B1Molded product production system
Publication Date: 2021.05.19 KIKUSUI SEISAKUSHO LTD
  • EP3225387B1 patent drawingFigure 1
  • EP3225387B1 patent drawingFigure 2
  • EP3225387B1 patent drawingFigure 3

AI summary

The invention provides a molded product production system including at least two measuring feeders (Z1a, Z1b, Z1c) configured to simultaneously adjust an amount of a discharged powdery material to a target value and feed the powdery material, a mixer (Z3, Z4) configured to mix at least two powdery materials fed from the measuring feeders (Z1a, Z1b, Z1c) to obtain mixed powdery materials, a filler (X) configured to fill, with the mixed powdery materials obtained by the mixer (Z3, Z4), a die bore (4) of a compression molding machine configured to compress a powdery material to mold a molded product, a sensor (S1, S2, S3, S4, S5) configured to measure a mixing degree of the mixed powdery materials obtained by the mixer (Z3, Z4), and a controller (C) configured to adjust an amount of at least one of the powdery materials fed by the measuring feeders (Z1a, Z1b, Z1c), or motion speed of a mixing member (Z34, Z35, Z44) configured to agitate powdery materials in the mixer (Z3, Z4) in accordance with the mixing degree of the mixed powdery materials measured by the sensor (S1, S2, S3, S4, S5).