Automated Contour Validation Using Statistical Tolerances

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Solution Overview

Problem

Current methods for evaluating the accuracy of delineated anatomies in computerized patient imaging are time-consuming, rely heavily on user expertise, and lack flexibility and customizability, leading to potential errors in medical procedures.

Innovation Solution

An automated quality control system that uses stored statistical data to validate the accuracy of delineated contours, with the ability to update and refine these standards based on individual performance, allowing for variances in targeted populations and image modalities.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If manual evaluation is used to assess delineated anatomy accuracy, then reliability of evaluation is improved, but time consumption increases

Engineering Contradiction:
Improveevaluation reliabilityVSAvoidtime consumption
Core Design Contradiction:
ReliabilityVSLoss of time

Solution Approach 1:

The patent introduces statistical data as an intermediary between manual evaluations and automated validation. The system collects manual evaluation results, processes them into statistical data defining acceptable tolerances, and uses this statistical data as a mediator to enable automated validation that maintains reliability while reducing time consumption.

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The system performs preliminary manual evaluations to build the statistical data database before automated validation can begin. This preliminary action creates the foundation of acceptable tolerance ranges that enable subsequent automated evaluations to be both fast and reliable.

Inventive Principle:
Principle #10Preliminary action

2Extent of automation

If atlas-based systems are used for validation, then automation is improved, but adaptability worsens

Engineering Contradiction:
Improvevalidation automationVSAvoidanatomical structure adaptability
Core Design Contradiction:
Extent of automationVSAdaptability or versatility

Solution Approach 1:

The system transitions from static atlas-based validation to dynamic statistical data-driven validation. The acceptable tolerances are not fixed in an atlas but are dynamically determined from collected evaluation data, allowing the system to adapt to new anatomical structures and populations while maintaining automation.

Inventive Principle:
Principle #15Dynamics

Solution Approach 2:

The patent changes the fundamental parameter from fixed atlas references to variable statistical tolerance ranges. By using parameter-based validation with adjustable acceptable tolerances derived from statistical data, the system achieves both automation and adaptability to diverse anatomical structures.

Inventive Principle:
Principle #35Parameter changes

3Ease of operation

If landmark-based similarity coefficients are used, then measurement simplicity is improved, but measurement precision worsens

Engineering Contradiction:
Improveevaluation simplicityVSAvoiddelineation accuracy
Core Design Contradiction:
Ease of operationVSMeasurement precision

Solution Approach 1:

The patent replaces the mechanical landmark-based measurement system with a statistical field-based validation system. Instead of measuring distances between discrete landmarks, the system uses statistical data to define acceptable tolerance ranges for anatomical structure delineation, achieving both simplicity and precision.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Data Source

PatentUS9626757B2System and method for the validation and quality assurance of computerized contours of human anatomy
Publication Date: 2017.04.18 WASHINGTON UNIV IN SAINT LOUIS
  • US9626757B2 patent drawing
  • US9626757B2 patent drawing
  • US9626757B2 patent drawing

AI summary

A system and method for validating the accuracy of delineated contours in computerized imaging using statistical data for generating assessment criterion that define acceptable tolerances for delineated contours, with the statistical data being conditionally updated and/or refined between individual processes for validating delineated contours to thereby adjust the tolerances defined by the assessment criterion in the stored statistical data, such that the stored statistical data is more closely representative of a target population. The present invention may be used to facilitate, as one example, on-line adaptive radiation therapy.