Nicotine Liquid Formulation with Controlled Acid–Nicotine Ratio
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Solution Overview
Problem
Existing nicotine liquid formulations provide inadequate sensory experience, particularly in terms of throat sensation and nicotine impact, and can adversely affect electronic devices due to high acidity, leading to potential device damage or undesirable compound generation.
Innovation Solution
A nicotine liquid formulation with a reduced molar ratio of primary acid to nicotine (0.5:1.0 to 0.85:1.0) and a pH range of 6 to 8, using organic acids like carboxylic acids, ensuring a significant presence of free nicotine base for enhanced taste satisfaction and throat sensation while minimizing device compatibility issues.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Manufacturing precision
If an equimolar ratio or greater amount of acid to nicotine is used to fully associate with nicotine molecules, then taste satisfaction and flavour perception are improved, but throat sensation and nicotine impact are reduced
Solution Approach 1:
The patent changes the molar ratio parameter from the conventional equimolar or greater (1:1 or higher) to a sub-stoichiometric range of 0.6:1 to 0.9:1 (acid:nicotine). This parameter change creates a balanced formulation where sufficient acid is present to improve taste satisfaction through nicotine salt formation, while enough free-base nicotine remains to provide adequate throat sensation and nicotine impact.
2Manufacturing precision
If a high concentration of free-acid is used in nicotine liquid formulation, then taste satisfaction is improved, but device components are adversely affected and damage occurs
Solution Approach 1:
The patent adjusts the acid concentration parameter by using a sub-stoichiometric molar ratio (0.6:1 to 0.9:1), which controls the amount of free-acid in the formulation. This reduces the acidity-related harmful effects on device components such as corrosion and degradation, while maintaining sufficient acid to provide taste satisfaction through nicotine salt formation.
3Manufacturing precision
If high acidity formulation is used to enhance flavour perception, then initial nicotine impact is improved, but device reliability is reduced
Solution Approach 1:
The patent optimizes the acidity parameter by implementing a sub-stoichiometric molar ratio of acid to nicotine (0.6:1 to 0.9:1). This creates a balanced pH level that provides sufficient flavour perception and initial nicotine impact through nicotine salt formation, while minimizing acidity-related damage to device components and maintaining device reliability.
Data Source
AI summary
A nicotine liquid formulation provides an improved sensory experience. Electronic cigarette cartridges including the nicotine liquid formulation, the use of the nicotine liquid formulation or the electronic cigarette cartridge in an electronic cigarette, electronic cigarettes including the nicotine liquid formulation or the electronic cigarette cartridge, and a method of generating an inhalable aerosol including using an electronic vaporization device having the nicotine liquid formulation are also provided.