Controlled Cooling Device for Selective Adipocyte Disruption

Resolve Bottlenecks,
Find Innovative Solutions
Generate Solutions

Solution Overview

Problem

Current methods for reducing subcutaneous fatty tissue are invasive and often cause collateral damage to the dermis and epidermis, and existing non-invasive methods struggle to selectively disrupt lipid-rich cells without harming surrounding non-lipid rich tissues.

Innovation Solution

A method and device that apply a controlled cooling element to create a temperature gradient to selectively disrupt lipid-rich cells while maintaining the skin temperature to avoid damage to non-lipid rich cells, using a cooling agent at specific temperatures to induce damage to adipocytes without affecting dermal and epidermal tissues.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If invasive methods (e.g., liposuction) are used to reduce subcutaneous fatty tissue, then productivity is improved, but object-generated harmful factors worsen due to excessive bleeding, pain, and infection risks

Engineering Contradiction:
Improvefat reduction efficiencyVSAvoidcollateral damage to dermis and epidermis
Core Design Contradiction:
ProductivityVSObject-generated harmful factors

Solution Approach 1:

The patent applies controlled cooling at specific temperature ranges (below 15°C, preferably below 10°C or 5°C) to selectively disrupt adipocytes while preserving other tissues. This temperature parameter change enables non-invasive fat reduction without the harmful effects of surgical procedures.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The cooling element is applied locally to specific treatment areas on the skin surface, creating localized temperature gradients that affect only the targeted subcutaneous adipose tissue while maintaining normal temperature and function of surrounding dermal and epidermal structures.

Inventive Principle:
Principle #3Local quality

2Productivity

If aggressive cooling is applied to disrupt lipid-rich cells, then productivity is improved, but object-affected harmful factors worsen due to damage to non-lipid rich cells

Engineering Contradiction:
Improveselective disruption of adipocytesVSAvoidinjury to dermal and epidermal tissues
Core Design Contradiction:
ProductivityVSObject-affected harmful factors

Solution Approach 1:

The patent identifies and applies specific temperature thresholds that selectively affect lipid-rich cells. By controlling the cooling temperature to remain above certain levels (avoiding excessive cold), the method achieves adipocyte disruption while preventing damage to non-lipid rich cells in the dermis and epidermis.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The cooling is applied to a greater extent than conventional methods (more aggressive cooling) but is carefully controlled to stop before causing damage to non-target tissues. This partial excessive action achieves better fat disruption while maintaining safety through precise temperature monitoring and control.

Inventive Principle:
Principle #16Partial or excessive action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The method effectively reduces subcutaneous adipose tissue by selectively disrupting lipid-rich cells while preserving the integrity of dermal and epidermal tissues, minimizing risks of injury and promoting health and cosmetic benefits.

Implementation Method 1

applying a cooling element proximal to the subject's skin to create a temperature gradient within a local region sufficient to selectively disrupt and thereby reduce the lipid-rich cells

Methodology Applied
Scientific EffectTemperature gradient: Temperature Gradient

Implementation Method 2

concurrently therewith maintain the subject's skin at a temperature wherein non lipid-rich cells proximate to the cooling element are not disrupted

Methodology Applied
Scientific EffectControlled cooling: Cooling

Data Source

PatentUS9308120B2Methods and devices for selective disruption of fatty tissue by controlled cooling
Publication Date: 2016.04.12 THE GENERAL HOSPITAL CORP
  • US9308120B2 patent drawing
  • US9308120B2 patent drawing
  • US9308120B2 patent drawing

AI summary

The present invention relates to methods for use in the selective disruption of lipid-rich cells by controlled cooling. The present invention further relates to a device for use in carrying out the methods for selective disruption of lipid-rich cells by controlled cooling.