Cooling Agent Formulation for Skin Compatibility
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Solution Overview
Problem
Existing cosmetic and dermatological preparations often suffer from stickiness, skin irritation, and limited cooling effects, with substances like ethanol and menthol derivatives being unsuitable due to their irritant potential and strong odor, and being poorly soluble in water, limiting their use in cosmetics and dermatics.
Innovation Solution
The use of 2-isopropyl-5-methyl-cyclohexanecarbonyl-D-alanine methyl ester combined with skin moisturizers such as glycerin and other polyhydric alcohols in a formulation that provides a pleasant cooling effect without stickiness, irritation, and is easy to produce, suitable for various cosmetic and dermatological applications.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Temperature
If ethanol or menthol derivatives are used as cooling agents, then cooling effect is achieved, but skin irritation and unpleasant odor occur
Solution Approach 1:
The patent changes the chemical parameter of the cooling agent from traditional ethanol or menthol derivatives to 2-isopropyl-5-methyl-cyclohexanecarbonyl-D-alanine methyl ester, which has different molecular structure and properties. This parameter change maintains the cooling effect while eliminating skin irritation and unpleasant odor, as the new compound interacts differently with skin receptors without causing irritation.
Solution Approach 2:
The patent uses a composite approach by combining 2-isopropyl-5-methyl-cyclohexanecarbonyl-D-alanine methyl ester with skin moisturizers in a formulated preparation. This composite formulation enhances skin compatibility and moisturization while maintaining the cooling effect, creating a synergistic product that addresses multiple requirements simultaneously.
2Quantity of substance
If polyhydric alcohols like glycerin are used for skin moisturization, then skin moisturization is improved, but stickiness increases and ease of distribution deteriorates
Solution Approach 1:
The patent modifies the physical parameter of the polyhydric alcohol by combining it with 2-isopropyl-5-methyl-cyclohexanecarbonyl-D-alanine methyl ester in specific proportions. This changes the overall viscosity and spreading characteristics of the formulation, reducing stickiness while maintaining moisturization effectiveness. The new compound acts as a viscosity modifier that improves ease of distribution.
Solution Approach 2:
The patent creates a composite formulation combining skin moisturizers (polyhydric alcohols) with 2-isopropyl-5-methyl-cyclohexanecarbonyl-D-alanine methyl ester. This composite approach allows the moisturizing agent to retain its hydrating properties while the combined formulation reduces the unwanted sticky feel and improves spreadability on the skin.
3Temperature
If ionic compounds or ammonium salts are used as cooling agents, then cooling effect is achieved, but solubility in water deteriorates
Solution Approach 1:
The patent changes the chemical parameter of the cooling agent from ionic compounds or ammonium salts to 2-isopropyl-5-methyl-cyclohowanecarbonyl-D-alanine methyl ester, which has superior water solubility. The molecular structure of the new compound allows it to dissolve readily in aqueous formulations, overcoming the solubility limitations of traditional ionic cooling agents and enabling broader cosmetic applications.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The formulation achieves excellent skin moisturization with a pleasant cooling effect, reduced stickiness, and improved skin compatibility, making it suitable for a wide range of applications including skin care, decorative cosmetics, and medical-pharmaceutical dosage forms.
Implementation Method 1
Use of so-called 'cooling agents' that interact with the skin's heat receptors and thus trigger a feeling of cold without generating a measurable physical cooling
Implementation Method 2
The use of skin moisturizers - polyhydric alcohols such as glycerin are often used
Data Source
AI summary
The invention relates to cosmetic or dermatological preparations with a content of 2-isopropyl-5- methyl-cyclohexanecarbonyl-D-alanine methyl ester and one or more skin moisturising agents.