Copper-Based Antibacterial Implant Coating via PVD

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Solution Overview

Problem

Existing antibacterial coatings for implants face challenges in balancing antibacterial activity with mechanical properties like hardness and cytotoxicity, particularly with silver, and in achieving effective production methods that do not increase manufacturing costs.

Innovation Solution

A copper-based antibacterial coating with additional components like Ti, Zr, Nb, Ta, Cr, Mo, W, Si, Al, applied using PVD processes, which maintains hardness and adhesion while controlling copper release to achieve antibacterial activity without cytotoxicity, using multilayer or single-layer configurations to manage copper concentration and release rate.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If silver is used in a coating for implants to achieve high antibacterial activity, then antibacterial performance is improved, but cytotoxicity increases

Engineering Contradiction:
Improveantibacterial activityVSAvoidcytotoxicity
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent changes the metal element from silver to copper, fundamentally altering the chemical properties. Copper provides sufficient antibacterial activity while having a higher cytotoxic threshold, thus resolving the contradiction between antibacterial performance and cytotoxicity

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent employs a thin copper-containing coating layer (1-10 μm) that provides temporary antibacterial protection during the critical healing period after implantation, then naturally degrades or is absorbed, avoiding long-term cytotoxic accumulation

Inventive Principle:
Principle #27Cheap short-living objects (Disposable)

2Reliability

If copper is added to coating to achieve antibacterial activity, then antibacterial performance is improved, but hardness decreases

Engineering Contradiction:
Improveantibacterial activityVSAvoidhardness
Core Design Contradiction:
ReliabilityVSStrength

Solution Approach 1:

The patent creates a composite coating system where copper is combined with other metals or ceramic materials (such as titanium, tantalum, or ceramic particles) to maintain the mechanical hardness while incorporating the antibacterial properties of copper

Inventive Principle:
Principle #40Composite materials

Solution Approach 2:

The copper content is optimized at the surface level where antibacterial activity is most needed, while the bulk material maintains its original high-hardness composition, achieving local functional differentiation without compromising overall mechanical properties

Inventive Principle:
Principle #3Local quality

3Strength

If PVD process is used to produce coating with good adhesion and hardness, then mechanical properties are improved, but antibacterial activity is insufficient

Engineering Contradiction:
Improveadhesion and hardnessVSAvoidantibacterial activity
Core Design Contradiction:
StrengthVSReliability

Solution Approach 1:

The patent merges the PVD deposition process (which provides excellent adhesion and hardness) with copper-containing materials (which provide antibacterial activity), combining two previously separate functional advantages into a single coating system

Inventive Principle:
Principle #5Merging (Combining)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The coating effectively reduces bacterial activity on implants, promoting better integration of new bone tissue and reducing post-surgical infection medication needs, with controlled copper release ensuring safety and efficiency in antibacterial performance.

Implementation Method 1

applied using PVD processes

Methodology Applied
Scientific EffectPhysical Vapour Deposition: Physical Vapour Deposition

Implementation Method 2

controlling copper release to achieve antibacterial activity without cytotoxicity

Methodology Applied
Scientific EffectIon release:

Data Source

PatentUS9107981B2Antibacterial coating for an implant and method for producing said coating
Publication Date: 2015.08.18 NEW YORK CITY DEPARTMENT OF TRANSPORTATION
  • US9107981B2 patent drawing
  • US9107981B2 patent drawing

AI summary

An antibacterial coating for an implant is provided that contains copper. A method of producing an antibacterial coating for an implant is also provided that includes the coating being applied by a PVD process and the layer generated by the PVD process includes a copper content.