Copper-Calcium Sulphate Feed Additive Reduces Toxicity

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Solution Overview

Problem

High doses of copper in animal feed lead to toxicity, nutritional imbalances, environmental pollution, and food safety concerns due to its growth-promoting effects exceeding nutritional needs and causing adverse health effects.

Innovation Solution

Copper-calcium sulphate is used as a feed additive, providing a low-dose, slow-release form of copper that meets nutritional needs, reduces toxicity, and maintains normal gut flora, acting as a broad-spectrum fungicide and growth promoter within the range of 1 to 30 ppm.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If high doses of copper (up to 250 mg/kg) are used in animal feed to achieve growth promotion effects, then animal growth is significantly improved, but copper toxicity damages animal organs and weakens immunity

Engineering Contradiction:
Improveanimal growth promotionVSAvoidcopper toxicity and organ damage
Core Design Contradiction:
ProductivityVSObject-affected harmful factors

Solution Approach 1:

The patent changes the chemical form of copper from conventional copper sulfate to copper-calcium sulphate complex, which alters the release characteristics and bioavailability of copper ions. This parameter change allows achieving growth promotion at lower doses (1-30 ppm) while reducing toxicity, as the complexed copper releases more slowly and is better regulated in the animal system

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The invention uses a composite copper-calcium sulphate material where copper is complexed with calcium sulphate. This composite structure provides controlled release of copper ions, maintaining effective concentrations for growth promotion while preventing toxic accumulation in animal organs, thus resolving the contradiction between productivity and harmful effects

Inventive Principle:
Principle #40Composite materials

2Productivity

If high doses of copper are used for growth promotion, then animal growth is enhanced, but excessive copper residues accumulate in animal tissues affecting food safety

Engineering Contradiction:
Improveanimal growthVSAvoidfood safety
Core Design Contradiction:
ProductivityVSReliability

Solution Approach 1:

By changing from conventional copper additives to copper-calcium sulphate complex, the patent modifies the absorption and retention characteristics of copper in animals. The complexed form results in lower tissue residues at effective growth promotion doses, ensuring food safety while maintaining productivity benefits

Inventive Principle:
Principle #35Parameter changes

3Productivity

If high doses of copper are used to achieve growth promotion, then copper's antimicrobial effects are enhanced, but microbial imbalance in animal guts causes diarrhea and vitamin B deficiencies

Engineering Contradiction:
Improvegrowth promotionVSAvoidgut microbial imbalance
Core Design Contradiction:
ProductivityVSObject-generated harmful factors

Solution Approach 1:

The patent changes the delivery form of copper to a complexed state that releases ions more gradually. This parameter change prevents sudden high concentrations of free copper ions in the gut that would disrupt microbial balance, while still providing sufficient copper for growth promotion and maintaining healthy gut flora

Inventive Principle:
Principle #35Parameter changes

4Productivity

If high doses of copper are used for growth promotion, then copper's protein coagulation effect is enhanced for mildew prevention, but long-term high-copper intake causes environmental pollution

Engineering Contradiction:
Improvegrowth promotion and mildew preventionVSAvoidenvironmental pollution
Core Design Contradiction:
ProductivityVSObject-generated harmful factors

Solution Approach 1:

By using copper-calcium sulphate complex instead of conventional copper salts, the patent reduces the total copper dosage required (to 1-30 ppm) while maintaining effectiveness. This parameter change in dosage and chemical form significantly reduces copper excretion and environmental pollution while preserving growth promotion and mildew prevention benefits

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Copper-calcium sulphate effectively promotes animal growth while reducing copper dosage by 50% to 70%, minimizing toxicity and pollution, and maintaining animal health by providing calcium and bactericidal effects, thus serving as a safer and more efficient alternative to high-copper preparations.

Implementation Method 1

Copper-calcium sulphate is used as a feed additive, providing a low-dose, slow-release form of copper

Methodology Applied
Scientific EffectSlow-release:

Implementation Method 2

copper-calcium sulphate showed a growth promoting effect equal to that of a high-copper intake with copper sulfate pentahydrate as the additive... maintaining normal gut flora

Methodology Applied
Scientific EffectBactericidal effect:

Implementation Method 3

A high dose of copper can be used in mildew prevention on animal feeds

Methodology Applied
Scientific EffectFungicidal effect:

Data Source

PatentUS11337443B2Use of copper-calcium sulphate as animal feed additive
Publication Date: 2022.05.24 GUANGZHOU INSIGHER BIOTECHNOLOGY CO LTD

AI summary

Provided is a method of using a copper-calcium sulphate as an animal feed additive. When used in animal breeding, a low dose of the copper-calcium sulphate can achieve the effect of that high dosage of copper sulphate achieve in the promotion of animal growth, and thus the copper-calcium sulphate can be used as an animal basic nutritional supplement to substitute low-copper preparations in the breeding of poultry, livestock or aquatic animals. Copper-calcium sulphate, used as a novel, efficient and safe feed additive in the feed processing industry and animal breeding industry, can reduce the dosage of copper ion by nearly 50-70% to achieve the same production performance, can significantly reduce the use of copper in animal husbandry, and can reduce the production costs, reduce the toxic side effects of a high level of copper, and reduce the environmental pollution, thus the copper-calcium sulphate is a copper compound with unique advantages.