Copper Ion Self-Assembled Complex for Sustained Antimicrobial Release
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Solution Overview
Problem
Existing technologies face challenges in sustaining the release of copper ions at a constant concentration, limiting their effectiveness as antibacterial and antiviral agents.
Innovation Solution
A self-assembled complex containing copper ions and ligands, which are reversibly assembled and degraded, allowing control over the self-degradation rate and active ingredient delivery by adjusting the constituent ingredients and blending ratios, forming shapes like needles, sea urchins, and spheres.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If copper ions are applied to places that people often come into contact with to release copper ions, then antibacterial and antiviral effects are achieved, but the release of copper ions cannot be sustained at a constant concentration
Solution Approach 1:
The patent applies preliminary action by pre-assembling copper ions with ligands (such as amino acids, nucleic acids, or their derivatives) to form stable complex structures before application. These pre-formed complexes are designed to gradually release copper ions over time, ensuring sustained antibacterial and antiviral effects rather than immediate but short-lived release.
Solution Approach 2:
The patent utilizes parameter changes by modifying the chemical structure of ligands (选择不同的氨基酸、核苷酸或其衍生物) and adjusting their ratios to control the degradation rate and copper ion release kinetics. By changing parameters such as ligand type, molecular weight, and composition ratio, the release profile can be optimized for sustained constant concentration delivery.
2Quantity of substance
If a technique for an antibacterial film containing copper is used, then copper ions can be released, but the technique cannot supply copper ions sustainably while maintaining a constant concentration
Solution Approach 1:
The patent employs composite materials by combining copper ions with organic ligands (amino acids, nucleic acids, or their derivatives) to form coordination complexes. These composite structures provide both the copper ion source and a controlled release mechanism through the ligand framework, enabling sustained release at constant concentration over extended periods.
Solution Approach 2:
The patent uses ligands as intermediaries between the copper ion source and the environment. These ligands mediate the release process by coordinating with copper ions and controlling their dissociation rate, thereby maintaining constant copper ion concentration in the surrounding environment over time rather than direct release from pure copper sources.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The complex provides sustained release of copper ions and active ingredients over 1 to 30 days, enhancing the delivery efficiency and effectiveness of antibacterial and antiviral agents.
Implementation Method 1
the ligands and the copper ions are reversibly self-assembled or self-degraded
Implementation Method 2
the self-degradation rate of the complex is adjusted by adjusting the constituent ingredients of the complex
Data Source
AI summary
Disclosed is a self-assembled complex containing copper ions, including: copper ions; and one or more ligands, in which the ligands and the copper ions are reversibly self-assembled or self-degraded, and when there are a plurality of types of ligands or a plurality of ligands, the shape of the self-assembled complex is formed differently depending on the blending ratio of the ligands.