Core Needle Biopsy Sample Holder for Multiple Sample Collection

Solution Overview

Problem

Existing core needle biopsy devices can only collect one tissue sample per insertion, while vacuum-assisted devices can collect multiple samples, but they lack the simplicity and smaller needle size advantages of core needle devices.

Innovation Solution

A core needle biopsy device designed to allow multiple sample collection through a combination of a piercer and cutter configuration, incorporating a tissue sample holder with features for efficient transfer of severed tissue samples using fluid-based extraction mechanisms.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If a core needle biopsy device uses a single piercer and cutting sheath configuration, then the device maintains simplicity and smaller needle size advantages, but it can only collect one tissue sample per insertion

Engineering Contradiction:

Improvenumber of samples collected per insertionVSAvoiddevice structure complexity

Core Design Contradiction:

ProductivityVSDevice complexity

Solution Approach 1:

The tissue sample holder is divided into multiple discrete tissue receiving notches (first notch, second notch, third notch) that can independently receive and store separate tissue samples. This segmentation allows multiple samples to be collected during a single insertion procedure while maintaining the simplicity of the core needle device structure.

Inventive Principle:

Principle #1Segmentation

Solution Approach 2:

The tissue sample holder with multiple notches is nested within the hollow cutter structure. The hollow cutter contains the tissue sample holder, which in turn contains multiple notches for sample storage. This nested configuration enables multiple sample collection capability while keeping the overall device structure compact and manageable.

Inventive Principle:

Principle #7Nested doll (Nesting)

2Loss of time

If a core needle biopsy device uses a single tissue receiving notch, then the device structure remains simple, but it requires multiple insertions to collect multiple tissue samples

Engineering Contradiction:

Improvetime required for multiple insertionsVSAvoidtissue sample holder structure

Core Design Contradiction:

Loss of timeVSDevice complexity

Solution Approach 1:

The tissue sample holder is divided into multiple discrete tissue receiving notches (first notch, second notch, third notch) that can independently receive and store separate tissue samples. This segmentation allows multiple samples to be collected during a single insertion procedure while maintaining the simplicity of the core needle device structure.

Inventive Principle:

Principle #1Segmentation

Solution Approach 2:

The tissue sample holder with multiple notches is pre-configured within the hollow cutter before insertion. This preliminary preparation enables the device to immediately receive and store multiple tissue samples during a single insertion, eliminating the need for multiple insertions and reducing procedure time.

Inventive Principle:

Principle #10Preliminary action

3Ease of operation

If multiple tissue samples are collected in a single notch, then the device structure remains simple, but sample management and differentiation become difficult

Engineering Contradiction:

Improvesample management efficiencyVSAvoidsample identification information

Core Design Contradiction:

Ease of operationVSLoss of information

Solution Approach 1:

The tissue sample holder is divided into multiple discrete tissue receiving notches (first notch, second notch, third notch) that can independently receive and store separate tissue samples. This segmentation allows multiple samples to be collected during a single insertion procedure while maintaining the simplicity of the core needle device structure.

Inventive Principle:

Principle #1Segmentation

Solution Approach 2:

Each tissue receiving notch has a specific location and orientation within the tissue sample holder, creating distinct spatial zones for sample storage. The first notch, second notch, and third notch are positioned differently, allowing easy differentiation and tracking of samples based on their location, thus maintaining sample identification information.

Inventive Principle:

Principle #3Local quality

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Enables single insertion with multiple sample collection, maintaining the advantages of core needle devices like simplicity and smaller needle size while improving sample management efficiency.

Implementation Method 1

a fluid source and a nozzle, the fluid source being configured to eject a liquid or gas from the nozzle and against the severed tissue sample to thereby propel the tissue sample into the sample chamber

Methodology Applied

Scientific EffectFluid propulsion: Jet

Data Source

PatentUS20250302454A1Sample management for core needle biopsy device

Publication Date: 2025.10.02 DEVICOR MEDICAL PRODUCTS INC

AI summary

A core needle biopsy device, including: a needle assembly, the needle assembly including a piercer and a hollow cutter, the piercer including a sharp distal tip and a notch proximal to the distal tip, the piercer being slidably disposed within the cutter to sever a tissue sample into the notch of the piercer; a drive assembly configured to selectively move the piercer and the cutter; and a tissue sample holder including a sample chamber, a fluid source, and a nozzle, the fluid source being configured to eject a liquid or gas from the nozzle and against a portion of the biopsy device to manipulate a severed tissue sample into the sample chamber.