Core-Shell Hydrogel Microfibers for Strong 3D Woven Structures

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Solution Overview

Problem

Microfibers made from hydrogel materials other than alginate gel have insufficient mechanical strength, making them unsuitable for producing woven fabrics with complex microstructures.

Innovation Solution

Coating microfibers with high-strength hydrogels like alginate gel or agarose gel to create a core-shell structure, significantly enhancing their mechanical strength and enabling the construction of three-dimensional structures such as woven fabrics, cylinders, or helical structures.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If microfibers are made from hydrogel materials other than alginate gel, then biocompatibility and biodegradability are improved, but mechanical strength deteriorates

Engineering Contradiction:
ImprovebiocompatibilityVSAvoidmechanical strength
Core Design Contradiction:
ReliabilityVSStrength

Solution Approach 1:

The patent creates a core-shell composite structure where a biocompatible hydrogel core (such as peptide hydrogel, collagen gel, or gelatin) is coated with an alginate gel shell. This composite structure combines the biocompatibility advantages of the inner hydrogel with the mechanical strength of the outer alginate shell, resolving the contradiction between biocompatibility and mechanical strength.

Inventive Principle:
Principle #40Composite materials

Solution Approach 2:

The patent applies different material properties to different parts of the microfiber structure. The inner core maintains biocompatible materials for cell interaction, while the outer shell uses high-strength alginate gel for structural support. This local differentiation allows each region to optimize its function without compromising the other.

Inventive Principle:
Principle #3Local quality

2Adaptability or versatility

If microfibers are made from hydrogel materials other than alginate gel, then material versatility is improved, but mechanical strength deteriorates

Engineering Contradiction:
Improvematerial versatilityVSAvoidmechanical strength
Core Design Contradiction:
Adaptability or versatilityVSStrength

Solution Approach 1:

The patent enables use of various hydrogel materials (peptide hydrogel, collagen gel, gelatin, fibrin gel) as core materials while maintaining structural integrity through the alginate shell. This composite approach provides material versatility for different biomedical applications while ensuring sufficient mechanical strength through the reinforcing shell structure.

Inventive Principle:
Principle #40Composite materials

Solution Approach 2:

The patent divides the microfiber into functional segments: an inner core for material versatility and biochemical functionality, and an outer shell for mechanical strength. This segmentation allows independent optimization of each segment's properties.

Inventive Principle:
Principle #1Segmentation

3Strength

If microfibers are coated with high strength hydrogel, then mechanical strength is improved, but device complexity is worsened

Engineering Contradiction:
Improvemechanical strengthVSAvoidstructure complexity
Core Design Contradiction:
StrengthVSDevice complexity

Solution Approach 1:

The patent uses a thin alginate gel shell to provide mechanical strength enhancement. This thin-film approach adds minimal structural complexity while achieving the desired strength improvement, as the shell is sufficiently thin to not significantly complicate the overall device structure.

Inventive Principle:
Principle #30Flexible shells and thin films

Solution Approach 2:

The core-shell composite structure provides a simple yet effective solution for enhancing mechanical strength. The straightforward two-layer design avoids complex multi-layer or heterogeneous structures, maintaining relative simplicity in fabrication and device architecture.

Inventive Principle:
Principle #40Composite materials

Data Source

PatentEP2489779B1Coated micro gel fibers
Publication Date: 2019.01.09 THE UNIV OF TOKYO
  • EP2489779B1 patent drawingFigure 1(A)~2B
  • EP2489779B1 patent drawingFigure 3
  • EP2489779B1 patent drawingFigure 4(A)~4(F)

AI summary

A microfiber showing improved mechanical strength, which comprises a micro gel fiber consisting of collagen gel or the like covered with high strength hydrogel such as alginate gel.