Core-Shell Micro Gel Fibers for Strong 3D Hydrogel Structures

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Solution Overview

Problem

Microfibers made from hydrogel materials other than alginate gel lack sufficient mechanical strength, making them unsuitable for constructing woven fabrics or complex three-dimensional structures.

Innovation Solution

Covering microfibers with a high-strength hydrogel, such as alginate gel or agarose gel, to create a core-shell structure that enhances mechanical strength, allowing for the construction of woven fabrics, cylinder structures, and other complex geometries.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Adaptability or versatility

If microfibers are made from hydrogel materials other than alginate gel, then the microfibers have good biocompatibility and flexibility, but they lack sufficient mechanical strength for constructing woven fabrics or complex three-dimensional structures

Engineering Contradiction:
ImprovebiocompatibilityVSAvoidmechanical strength
Core Design Contradiction:
Adaptability or versatilityVSStrength

Solution Approach 1:

The invention creates a core-shell composite microfiber structure where a weak but biocompatible hydrogel core is coated with a strong alginate gel shell. This composite structure combines the advantages of both materials: the core provides biocompatibility and flexibility while the shell provides mechanical strength, enabling the microfibers to be used for constructing woven fabrics and complex three-dimensional structures.

Inventive Principle:
Principle #40Composite materials

2Strength

If microfibers are made from alginate gel, then they have sufficient mechanical strength, but they limit the choice of hydrogel materials with specific functional properties

Engineering Contradiction:
Improvemechanical strengthVSAvoidmaterial selection flexibility
Core Design Contradiction:
StrengthVSAdaptability or versatility

Solution Approach 1:

The invention divides the microfiber into two functional segments: a core made from various biocompatible hydrogel materials (such as collagen, gelatin, or peptide hydrogels) that provide specific functional properties, and a shell made from alginate gel that provides mechanical strength. This segmentation allows independent optimization of each component's properties.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The alginate gel shell serves as a universal strengthening layer that can be applied to different types of hydrogel cores with various functional properties. This multi-functional approach allows the same shell material to enhance different core materials, providing both structural support and material diversity.

Inventive Principle:
Principle #6Universality (Multi-functionality)

3Strength

If a core-shell structure is created by coating microfibers with alginate gel, then mechanical strength is remarkably increased, but the structure becomes more complex

Engineering Contradiction:
Improvemechanical strengthVSAvoidstructural complexity
Core Design Contradiction:
StrengthVSDevice complexity

Solution Approach 1:

The invention uses a thin alginate gel shell to coat the microfiber core, providing mechanical strength while maintaining a relatively simple overall structure. The shell is flexible and conformal, adapting to the core's shape without adding significant structural complexity. This approach achieves strength enhancement through a minimalistic coating strategy rather than complex internal reinforcement.

Inventive Principle:
Principle #30Flexible shells and thin films

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The microfibers with a core-shell structure exhibit superior mechanical strength, enabling the creation of robust three-dimensional structures like woven fabrics, tubes, and cell structures, which can be used for cell culture and tissue engineering applications.

Implementation Method 1

a microfiber consisting of a micro gel fiber covered with a high strength hydrogel, wherein the micro gel fiber is a fiber comprising a hydrogel as a base material

Methodology Applied
Scientific EffectGelation: Gel

Data Source

PatentUS8785195B2Covered micro gel fiber
Publication Date: 2014.07.22 THE UNIV OF TOKYO
  • US8785195B2 patent drawing
  • US8785195B2 patent drawing
  • US8785195B2 patent drawing

AI summary

A microfiber showing improved mechanical strength, which comprises a micro gel fiber consisting of collagen gel or the like covered with high strength hydrogel such as alginate gel.