Cored Tissue Cavity Therapy Delivery for Precise Lesion Removal

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Solution Overview

Problem

Current methods for removing tissue, particularly in cases of cancerous lesions in the lungs, are invasive, require extensive surgery, and often result in substantial recovery times and complications, with diagnostic accuracy limited by the small sample sizes obtained from needle biopsies.

Innovation Solution

A method and system for removing a core of tissue using a tissue resection device, which includes anchoring to the lesion, creating a channel, ligating the tissue core, amputating it, and delivering localized treatments through a sleeve, allowing for precise removal and analysis of the entire lesion.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If needle biopsy is used to obtain tissue samples, then diagnostic sampling can be performed, but the sample size is small and diagnostic accuracy is limited

Engineering Contradiction:
Improvediagnostic accuracyVSAvoidtissue sample size
Core Design Contradiction:
Measurement precisionVSQuantity of substance

Solution Approach 1:

The patent extracts the entire tissue core or lesion from the body using a coring apparatus rather than taking small needle samples. The coring device removes a cylindrical core of tissue that contains the entire lesion, providing sufficient material for comprehensive diagnostic analysis while minimizing the need for multiple sampling procedures.

Inventive Principle:
Principle #2Taking out (Extraction)

2Reliability

If extensive surgery is performed to remove cancerous tissue, then complete lesion removal is achieved, but recovery time is extended and complications increase

Engineering Contradiction:
Improvelesion removal completenessVSAvoidrecovery time
Core Design Contradiction:
ReliabilityVSLoss of time

Solution Approach 1:

The patent extracts the entire lesion or tissue core in a single minimally invasive procedure using a coring apparatus. This approach removes the need for extensive surgical resection while achieving complete lesion removal, thereby significantly reducing recovery time and surgical complications.

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The coring apparatus serves as an intermediary tool that enables complete lesion removal without requiring traditional extensive surgery. The device acts as a mediator between minimally invasive access and complete tissue removal, achieving reliable lesion excision through a small access point.

Inventive Principle:
Principle #24Intermediary (Mediator)

3Reliability

If traditional surgery is used to remove tissue, then complete removal is achieved, but healthy tissue is substantially removed along with the lesion

Engineering Contradiction:
Improvelesion removal completenessVSAvoidhealthy tissue loss
Core Design Contradiction:
ReliabilityVSLoss of substance

Solution Approach 1:

The patent applies local quality by using a coring apparatus that removes only the specific cylindrical core containing the lesion while preserving the surrounding healthy tissue. The coring device is designed to extract tissue from a localized region without requiring wide surgical margins, thereby maintaining the integrity and function of adjacent healthy structures.

Inventive Principle:
Principle #3Local quality

Solution Approach 2:

The patent extracts only the necessary tissue core containing the lesion rather than removing large portions of surrounding healthy tissue. This selective extraction approach achieves complete lesion removal while minimizing collateral damage to healthy structures.

Inventive Principle:
Principle #2Taking out (Extraction)

4Reliability

If multiple procedures are performed for diagnosis and treatment, then comprehensive care is provided, but the number of interventions increases and recovery time extends

Engineering Contradiction:
Improvecomprehensive diagnostic and treatment careVSAvoidnumber of procedures
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent merges diagnostic sampling and therapeutic treatment into a single integrated procedure. The coring apparatus both obtains sufficient tissue for comprehensive diagnostic analysis and removes the entire lesion or provides access for immediate localized treatment, eliminating the need for separate diagnostic and therapeutic interventions.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The coring apparatus serves multiple functions: it performs diagnostic tissue sampling, complete lesion removal, and creates access for localized treatment delivery. This multi-functional device consolidates what would traditionally require multiple separate procedures into a single intervention.

Inventive Principle:
Principle #6Universality (Multi-functionality)

Data Source

PatentUS20250312057A1Methods and devices for delivering cancer therapy to a target tissue site via a cored tissue cavity
Publication Date: 2025.10.09 PRANA THORACIC INC
  • US20250312057A1 patent drawing
  • US20250312057A1 patent drawing
  • US20250312057A1 patent drawing

AI summary

A method for delivering cancer therapy may comprise introducing a tissue resection device to the tissue site, using the tissue resection device to create a core of tissue, removing at least a portion of the core of tissue from the body to create a tissue cavity, and performing therapeutic management of malignant tissue via the tissue cavity.