Replaceable Coriolis Measuring Tube Layout for Self-Emptying
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Solution Overview
Problem
Existing process monitoring systems for pharmaceutical bioprocessing applications do not effectively integrate Coriolis flow meters for self-emptying of replaceable measuring tubes, leading to inefficiencies and potential contamination risks.
Innovation Solution
A process monitoring device with a modular design comprising a measuring tube module and a receptacle module, where the measuring tube module is mechanically connectable to the receptacle module, allowing for easy replacement and ensuring minimal dead volume, facilitated by an inclination body that ensures self-emptying and sealing, and a fastening system that simplifies assembly and reduces mechanical stress on the housing.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Ease of operation
If measuring tubes are made replaceable for easy cleaning and contamination prevention, then ease of operation is improved, but device complexity increases due to the need for connection and sealing mechanisms
Solution Approach 1:
The flow meter is divided into separate modules: a disposable measuring tube module and a reusable receiver module. This segmentation allows the measuring tube to be easily replaced while keeping the main device simple and reusable, resolving the contradiction between ease of replacement and device complexity.
Solution Approach 2:
The measuring tube module is designed to nest within the receiver module, with the measuring tube inserted into a receptacle in the receiver. This nested structure provides secure connection and sealing while maintaining simplicity in both modules, enabling easy replacement without complex external mechanisms.
2Device complexity
If the measuring tube is oriented horizontally for compact design, then device complexity is reduced, but dead volume increases leading to contamination risks
Solution Approach 1:
The receptacle in the receiver module is oriented at an angle (e.g., 45 degrees) relative to the horizontal measuring tube, creating a downward slope toward the discharge end. This angular orientation in a different dimension allows gravity to drain residual medium completely while maintaining compact horizontal footprint, reducing dead volume without increasing overall device complexity.
3Manufacturing precision
If traditional flange connections are used for Coriolis flow meters, then manufacturing precision is maintained, but ease of operation deteriorates due to complex assembly and sterilization requirements
Solution Approach 1:
The measuring tube module is designed as a disposable component that is pre-sterilized and sealed. It connects to the reusable receiver module through simple mechanical interfaces without requiring complex flange assemblies, traditional gaskets, or multi-step sterilization procedures. This disposable approach maintains connection precision while dramatically simplifying assembly and sterilization operations.
4Reliability
If the receptacle extends into the housing interior for secure mounting, then reliability is improved, but ease of repair worsens due to limited access
Solution Approach 1:
The receptacle is pre-configured with mounting features (such as threads, lugs, or bayonet connectors) that engage with corresponding features in the housing interior. This preliminary design of mounting interfaces allows the receptacle to be securely mounted during assembly while enabling quick removal and reinstallation during maintenance, resolving the contradiction between secure mounting and ease of repair.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The solution enables efficient self-emptying of measuring tubes with minimal residual volume, simplifies assembly and maintenance, reduces contamination risks, and maintains measurement accuracy while allowing for easy retrofitting of existing systems.
Implementation Method 1
the receptacle module is arranged in the cover opening in such a manner that the receiving direction has a vectorial portion with a direction opposite to the direction of gravity
Data Source
AI summary
A process monitoring device includes: a measuring tube arrangement including a measuring tube; a receptacle module including a receptacle, wherein the measuring tube module is insertable into the receptacle and releasably mechanically connectable to the receptacle module; and a system for biotechnological applications, wherein the system includes a housing with a wall delimiting an interior, the wall having a cover with an opening, wherein the receptacle extends through the opening into the interior in a receiving direction, wherein the receptacle module is arranged in the opening that the receiving direction has a vector component opposite to the direction of gravity, such that a dead volume in the measuring tube and/or in a distributor piece which is attached to the measuring tube, when the measuring tube module is empty, is less than 20%.


