Hybrid Corn CH010994 Male Sterility Genetic Stability

Resolve Bottlenecks,
Find Innovative Solutions
Generate Solutions

Solution Overview

Problem

Current corn breeding techniques face challenges in developing hybrid varieties that combine desirable traits such as high yield, disease resistance, and uniformity, while maintaining genetic stability and avoiding self-pollination, which limits the introduction of new genetic modifications and traits.

Innovation Solution

The development of the hybrid corn variety CH010994, which incorporates a cytoplasmic or nuclear factor for male sterility, genetic modifications for herbicide resistance, and disease resistance, and a method for crossing plants to prevent self-pollination, allowing for the introduction of traits like waxy starch and altered metabolism through genetic transformation techniques.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Stability of the object's composition

If self-pollination is used to maintain genetic stability, then genetic uniformity is improved, but the introduction of new genetic modifications and traits is limited

Engineering Contradiction:
Improvegenetic stabilityVSAvoidintroduction of new traits
Core Design Contradiction:
Stability of the object's compositionVSAdaptability or versatility

Solution Approach 1:

The patent applies preliminary action by creating male-sterile inbred lines before hybrid development, which prevents self-pollination in the F1 generation and ensures that only controlled cross-pollination occurs. This preliminary preparation enables the introduction of new genetic modifications while maintaining genetic stability in the hybrid population.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The patent uses an intermediary approach by introducing male sterility genes as a controlling mechanism. These genes act as mediators that prevent self-pollination and ensure that only controlled cross-pollination between specific inbred lines occurs, thereby enabling the introduction of new traits while maintaining genetic uniformity in the hybrid.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Adaptability or versatility

If cross-pollination is used to introduce new traits, then genetic diversity is improved, but genetic uniformity and stability are reduced

Engineering Contradiction:
Improvegenetic diversityVSAvoidgenetic uniformity
Core Design Contradiction:
Adaptability or versatilityVSStability of the object's composition

Solution Approach 1:

The patent applies local quality by creating male-sterile inbred lines with specific genetic modifications at particular loci. These inbred lines maintain uniformity within themselves while being designed to complement each other in the cross, allowing the introduction of specific new traits while maintaining overall genetic uniformity in the F1 hybrid.

Inventive Principle:
Principle #3Local quality

Solution Approach 2:

The patent uses preliminary action by developing male-sterile inbred lines before the actual cross-pollination. This preliminary development ensures that the inbred lines are genetically uniform and stable, so that when cross-pollination occurs, the F1 hybrid maintains genetic uniformity while incorporating the desired new traits from the male-sterile parent.

Inventive Principle:
Principle #10Preliminary action

3Productivity

If male sterility is introduced to prevent self-pollination, then hybrid seed production is improved, but the complexity of the breeding system increases

Engineering Contradiction:
Improvehybrid seed productionVSAvoidbreeding system complexity
Core Design Contradiction:
ProductivityVSDevice complexity

Solution Approach 1:

The patent applies self-service by using cytoplasmic male sterility (CMS) systems where the male sterility is inherited through the cytoplasm rather than requiring complex nuclear gene interactions. This self-service mechanism automatically prevents self-pollination without requiring additional control measures, simplifying the breeding system while improving hybrid seed production.

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The patent uses parameter changes by utilizing cytoplasmic male sterility, which changes the mode of inheritance from nuclear to cytoplasmic. This parameter change simplifies the breeding system by eliminating the need for complex nuclear gene interactions and automatic control mechanisms, while still achieving effective prevention of self-pollination.

Inventive Principle:
Principle #35Parameter changes

4Stability of the object's composition

If inbred lines are developed through self-pollination, then genetic uniformity is improved, but the time to crop maturity is extended

Engineering Contradiction:
Improvegenetic uniformityVSAvoidtime to crop maturity
Core Design Contradiction:
Stability of the object's compositionVSLoss of time

Solution Approach 1:

The patent applies preliminary action by developing male-sterile inbred lines before the hybrid development phase. This preliminary action allows the inbred lines to be established and tested independently, so that when the actual hybrid cross occurs, the time to crop maturity is not extended by additional self-pollination cycles.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The patent uses an intermediary approach by introducing male sterility as a controlling mechanism that allows the use of existing inbred lines without requiring further self-pollination. This intermediary mechanism enables the direct production of F1 hybrids from pre-existing inbred lines, thereby reducing the time needed to achieve genetic uniformity while maintaining it.

Inventive Principle:
Principle #24Intermediary (Mediator)

Data Source

PatentUS11871715B2Plants and seeds of hybrid corn variety CH010994
Publication Date: 2024.01.16 MONSANTO TECHNOLOGY LLC

AI summary

According to the invention, there is provided seed and plants of the hybrid corn variety designated CH010994. The invention thus relates to the plants, seeds and tissue cultures of the variety CH010994, and to methods for producing a corn plant produced by crossing a corn plant of variety CH010994 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH010994.