Hybrid Corn CH011060 Cytoplasmic Male Sterility Breeding

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Solution Overview

Problem

Current corn breeding techniques face challenges in developing hybrid varieties that combine desirable traits such as high yield, disease resistance, and uniformity, while maintaining genetic stability and avoiding self-pollination, which limits the efficiency of hybrid seed production.

Innovation Solution

The development of the hybrid corn variety CH011060, which incorporates genetic modifications and cytoplasmic male sterility traits to prevent self-pollination, along with specific genetic loci conferring herbicide resistance, disease resistance, and other desirable characteristics, using advanced breeding methods and genetic transformation techniques like CRISPR-Cas systems.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If traditional self-pollination breeding methods are used, then genetic stability is maintained, but hybrid seed production efficiency is limited due to inability to prevent self-pollination

Engineering Contradiction:
Improvehybrid seed production efficiencyVSAvoidgenetic stability
Core Design Contradiction:
ProductivityVSStability of the object's composition

Solution Approach 1:

The patent extracts and removes the male fertility function from the plant by introducing cytoplasmic male sterility (CMS) traits. This prevents self-pollination by eliminating pollen production, thereby forcing cross-pollination and improving hybrid seed production efficiency while maintaining genetic stability through controlled breeding.

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The patent uses genetic modifiers and restorer genes as intermediaries to control the male sterility phenotype. These genetic elements mediate between the CMS trait and the desired fertility outcome, allowing precise control over pollination behavior while maintaining genetic stability across generations.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Adaptability or versatility

If multiple desirable traits are combined in a single hybrid variety, then agronomic quality and yield improve, but breeding complexity and time required increase

Engineering Contradiction:
Improveagronomic qualityVSAvoidbreeding program complexity
Core Design Contradiction:
Adaptability or versatilityVSDevice complexity

Solution Approach 1:

The patent applies preliminary action by pre-developing stable inbred parental lines with specific desirable traits (disease resistance, yield components, stress tolerance) before hybridization. This preparatory work organizes genetic material in advance, reducing breeding program complexity when combining multiple traits in the final hybrid variety.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The patent segments the breeding process into distinct phases: developing inbred parents with specific traits, introducing CMS markers for controlled hybridization, and finally combining traits in the hybrid variety. This segmentation of the breeding program makes complex multi-trait development more manageable and systematic.

Inventive Principle:
Principle #1Segmentation

3Ease of operation

If cytoplasmic male sterility is introduced to prevent self-pollination, then cross-pollination control improves, but genetic uniformity may be affected

Engineering Contradiction:
Improvecross-pollination controlVSAvoidgenetic uniformity
Core Design Contradiction:
Ease of operationVSStability of the object's composition

Solution Approach 1:

The patent uses cytoplasmic male sterility markers as feedback mechanisms to monitor and ensure genetic uniformity in hybrid populations. These markers provide visible or detectable indicators that allow breeders to verify proper cross-pollination and maintain genetic uniformity while benefiting from improved cross-pollination control.

Inventive Principle:
Principle #23Feedback

Data Source

PatentUS11234399B1Plants and seeds of hybrid corn variety CH011060
Publication Date: 2022.02.01 MONSANTO TECHNOLOGY LLC

AI summary

According to the invention, there is provided seed and plants of the hybrid corn variety designated CH011060. The invention thus relates to the plants, seeds and tissue cultures of the variety CH011060, and to methods for producing a corn plant produced by crossing a corn plant of variety CH011060 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH011060.