Hybrid Corn CH011132 Cytoplasmic Male Sterility Seed Production

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Solution Overview

Problem

Current corn breeding techniques face challenges in developing hybrid varieties that combine desirable traits such as high yield, disease resistance, and uniformity, while maintaining genetic stability and avoiding self-pollination, which limits the efficiency of trait introduction and hybrid seed production.

Innovation Solution

The development of the hybrid corn variety CH011132, which incorporates genetic modifications and cytoplasmic male sterility to prevent self-pollination, along with specific traits like herbicide resistance and disease resistance, using techniques like genome editing and backcrossing to introduce desired loci, and tissue culture methods for regenerating plants with consistent characteristics.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If conventional breeding methods are used to develop hybrid corn varieties, then genetic diversity can be introduced, but self-pollination occurs which reduces hybrid seed production efficiency

Engineering Contradiction:
Improvehybrid seed production efficiencyVSAvoidprevention of self-pollination
Core Design Contradiction:
ProductivityVSReliability

Solution Approach 1:

The patent extracts and removes the male fertility function from the hybrid corn plant by introducing cytoplasmic male sterility (CMS). This eliminates the ability of the hybrid plant to produce viable pollen, thereby completely preventing self-pollination and ensuring 100% cross-pollination in hybrid seed production fields.

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The patent uses a restorer line as an intermediary to control pollen fertility. The restorer line contains nuclear restorer genes that can restore male fertility when crossed with CMS hybrid plants. This intermediary mechanism allows controlled production of hybrid seeds while preventing unwanted self-pollination.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Adaptability or versatility

If multiple desirable traits are combined in a single hybrid variety, then agronomic quality improves, but breeding complexity increases

Engineering Contradiction:
Improveagronomic qualityVSAvoidbreeding program complexity
Core Design Contradiction:
Adaptability or versatilityVSDevice complexity

Solution Approach 1:

The patent creates a universal hybrid corn variety CH011132 that simultaneously provides multiple functions: high yield, disease resistance, herbicide tolerance, and improved agronomic quality. This multi-functional hybrid consolidates multiple desirable traits into a single variety, reducing the need for multiple separate breeding programs.

Inventive Principle:
Principle #6Universality (Multi-functionality)

Solution Approach 2:

The patent merges multiple breeding lines and traits into a single hybrid variety. By combining the CMS trait with disease resistance genes, herbicide tolerance genes, and yield-improving genes in one hybrid package, the breeding program complexity is reduced while delivering comprehensive agronomic improvement.

Inventive Principle:
Principle #5Merging (Combining)

3Productivity

If genetic modifications are introduced to prevent self-pollination, then hybrid seed production efficiency improves, but genetic stability may be compromised

Engineering Contradiction:
Improvehybrid seed production efficiencyVSAvoidgenetic stability
Core Design Contradiction:
ProductivityVSStability of the object's composition

Solution Approach 1:

The patent employs cytoplasmic male sterility which is a self-sustaining genetic mechanism. The CMS trait is inherited through the cytoplasm (mitochondrial DNA) and automatically prevents self-pollination in all hybrid plants without requiring external management or monitoring, ensuring both high productivity and genetic stability.

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The patent uses a feedback mechanism where the CMS trait and restorer genes interact to control pollen fertility. The presence or absence of restorer genes in the pollen parent provides feedback control over whether the hybrid will be fertile or sterile, allowing precise control of hybrid seed production while maintaining genetic stability through predictable inheritance patterns.

Inventive Principle:
Principle #23Feedback

Data Source

PatentUS11419286B2Plants and seeds of hybrid corn variety CH01132
Publication Date: 2022.08.23 MONSANTO TECHNOLOGY LLC

AI summary

According to the invention, there is provided seed and plants of the hybrid corn variety designated CH011132. The invention thus relates to the plants, seeds and tissue cultures of the variety CH011132, and to methods for producing a corn plant produced by crossing a corn plant of variety CH011132 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH011132.