Hybrid Corn Pollination Control Using Cytoplasmic Male Sterility

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Solution Overview

Problem

Existing corn breeding techniques struggle to develop hybrids with uniformity and desirable traits such as increased yield, disease resistance, and improved agronomic qualities while maintaining genetic stability and efficiency in hybrid seed production.

Innovation Solution

The development of the hybrid corn variety CH010502, which incorporates cytoplasmic or nuclear factors for male sterility, genetic modifications for traits like herbicide resistance and disease resistance, and a method for controlled cross-pollination using emasculation and bagging techniques to produce uniform hybrid seeds.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Manufacturing precision

If traditional corn breeding techniques are used, then hybrid seed production can be maintained, but uniformity and desirable traits such as increased yield and disease resistance are difficult to achieve simultaneously

Engineering Contradiction:
ImproveuniformityVSAvoidyield
Core Design Contradiction:
Manufacturing precisionVSProductivity

Solution Approach 1:

The patent applies parameter changes by utilizing cytoplasmic male sterility (CMS) systems with specific mitochondrial genomes (e.g., W, T, or G types) combined with nuclear restorer genes. This genetic parameter modification enables controlled pollination to achieve uniform F1 hybrid seeds while maintaining high yield potential through heterosis effects.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent employs cytoplasmic male sterility as an intermediary mechanism to control pollination. The CMS system acts as a mediator between the female parent (lacking functional pollen) and the male parent (providing pollen), enabling precise control over which plants are pollinated and thus ensuring uniformity in the F1 hybrid generation while maintaining high yield.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Productivity

If cytoplasmic male sterility factors are introduced to control pollination, then hybrid seed production efficiency is improved, but genetic stability and complexity increase

Engineering Contradiction:
Improvehybrid seed production efficiencyVSAvoidgenetic complexity
Core Design Contradiction:
ProductivityVSDevice complexity

Solution Approach 1:

The patent segments the control of male sterility into two independent components: cytoplasmic (mitochondrial) factors and nuclear restorer genes. This segmentation allows the cytoplasmic component to provide consistent male sterility while the nuclear component can be selectively introduced to restore fertility in specific lines, thereby controlling pollination efficiency without creating uncontrollable genetic complexity.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent utilizes maintaining lines that are cytoplasmically identical to the sterile line but lack the nuclear restorer genes. These maintaining lines serve as copies that propagate the cytoplasmic sterility without introducing additional nuclear complexity, allowing efficient production of uniform F1 hybrids while keeping the genetic system manageable through replication of the cytoplasmic genome.

Inventive Principle:
Principle #26Copying

3Reliability

If multiple genetic modifications are incorporated to achieve desired traits, then disease resistance and agronomic qualities improve, but breeding time and complexity increase

Engineering Contradiction:
Improvedisease resistanceVSAvoidbreeding time
Core Design Contradiction:
ReliabilityVSLoss of time

Solution Approach 1:

The patent applies preliminary action by developing and characterizing multiple cytoplasmic male sterility systems (W, T, G types) and their corresponding maintaining lines before actual hybrid seed production. This pre-characterization of cytoplasmic genomes and their stability across generations allows breeders to select appropriate CMS systems in advance, reducing breeding time when producing disease-resistant hybrids with multiple genetic modifications.

Inventive Principle:
Principle #10Preliminary action

Data Source

PatentUS12628769B2Plants and seeds of hybrid corn variety CH010502
Publication Date: 2026.05.19 MONSANTO TECHNOLOGY LLC

AI summary

According to the disclosure, there is provided seed and plants of the hybrid corn variety designated CH010502. The disclosure thus relates to the plants, seeds, and tissue cultures of the variety CH010502, and to methods for producing a corn plant produced by crossing a corn plant of variety CH010502 with itself or with another corn plant, such as a plant of another variety. The disclosure further relates to genetic complements of plants of variety CH010502.