Hybrid Corn Inbred Line Strategy for Stable Trait Uniformity

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Solution Overview

Problem

Existing corn breeding techniques struggle to develop hybrids with uniformity and stability, incorporating desirable traits such as yield, disease resistance, and drought tolerance, while maintaining genetic diversity and efficiency in pollination processes.

Innovation Solution

The development of the hybrid corn variety CH010451, which includes genetic modifications for traits like male sterility, herbicide resistance, and disease resistance, achieved through methods like backcrossing and genetic transformation using engineered nucleases, ensuring uniformity and stability.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Stability of the object's composition

If traditional corn breeding techniques are used, then genetic diversity is maintained, but uniformity and stability of hybrid traits are difficult to achieve

Engineering Contradiction:
Improveuniformity and stability of hybrid traitsVSAvoidbreeding process complexity
Core Design Contradiction:
Stability of the object's compositionVSDevice complexity

Solution Approach 1:

The patent applies preliminary action by developing and utilizing inbred lines with stable, uniform genetic composition before creating hybrids. The inbred lines are prepared in advance through multiple generations of self-pollination and selection, ensuring genetic uniformity is established before the hybridization step. This preliminary preparation of genetically stable parent lines directly enables the achievement of uniform and stable hybrid traits without requiring complex breeding processes during hybrid production.

Inventive Principle:
Principle #10Preliminary action

2Stability of the object's composition

If cross-pollination is used to create hybrids, then genetic diversity is increased, but uniformity in hybrid population is reduced

Engineering Contradiction:
Improveuniformity in hybrid populationVSAvoidgenetic diversity
Core Design Contradiction:
Stability of the object's compositionVSQuantity of substance

Solution Approach 1:

The patent applies local quality by creating hybrids from highly uniform inbred lines that have been selectively bred for specific local genetic characteristics. Each inbred line is developed with a specific genetic composition optimized for particular traits, and when these uniformly composed inbreds are crossed, the resulting hybrid population achieves uniformity. The local quality of the inbred parent lines is what enables uniform hybrid production, effectively managing the balance between genetic diversity and uniformity.

Inventive Principle:
Principle #3Local quality

3Stability of the object's composition

If inbred lines are developed through self-pollination, then genetic uniformity is achieved, but time to crop maturity is extended

Engineering Contradiction:
Improvegenetic uniformity of inbred linesVSAvoidtime to crop maturity
Core Design Contradiction:
Stability of the object's compositionVSLoss of time

Solution Approach 1:

The patent applies preliminary action by pre-developing the inbred lines through multiple generations of self-pollination and selection before the actual hybrid production. This preliminary development of genetically uniform inbred lines is performed in advance, allowing the hybridization process to proceed more efficiently. The time investment in preparing uniform inbred parents is made beforehand, enabling faster and more uniform hybrid crop maturity without compromising genetic uniformity.

Inventive Principle:
Principle #10Preliminary action

4Adaptability or versatility

If multiple breeding methods are combined, then desirable traits are incorporated, but breeding process efficiency is reduced

Engineering Contradiction:
Improveincorporation of desirable traitsVSAvoidbreeding process efficiency
Core Design Contradiction:
Adaptability or versatilityVSProductivity

Solution Approach 1:

The patent applies merging (combining) by integrating multiple breeding approaches - specifically combining self-pollination for inbred line development with controlled cross-pollination for hybrid creation. The method merges the advantages of both techniques: self-pollination provides genetic uniformity and stability, while controlled cross-pollination introduces desired traits and creates heterosis. This merged approach efficiently incorporates multiple desirable traits into hybrids while maintaining breeding process effectiveness through systematic integration of the two pollination methods.

Inventive Principle:
Principle #5Merging (Combining)

Data Source

PatentUS12588623B2Plants and seeds of hybrid corn variety CH010451
Publication Date: 2026.03.31 MONSANTO TECHNOLOGY LLC

AI summary

According to the disclosure, there is provided seed and plants of the hybrid corn variety designated CH010451. The disclosure thus relates to the plants, seeds, and tissue cultures of the variety CH010451, and to methods for producing a corn plant produced by crossing a corn plant of variety CH010451 with itself or with another corn plant, such as a plant of another variety. The disclosure further relates to genetic complements of plants of variety CH010451.