Corn Inbred Line Breeding for Uniform and Stable Hybrids

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Solution Overview

Problem

Existing corn breeding methods struggle to develop uniform hybrids with desirable traits such as greater yield, better stalks, resistance to pests and diseases, and tolerance to environmental stressors, leading to unpredictable performance.

Innovation Solution

The development of the corn variety CV622763, which is homozygous and includes genetic modifications for traits like herbicide tolerance, insect resistance, and cytoplasmic male sterility, achieved through techniques like backcrossing and genetic transformation, ensuring uniformity and stability.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Adaptability or versatility

If cross-pollination is used to create genetic diversity, then adaptability improves, but uniformity deteriorates

Engineering Contradiction:
Improvegenetic diversityVSAvoiduniformity
Core Design Contradiction:
Adaptability or versatilityVSStability of the object's composition

Solution Approach 1:

The breeding program segments the population into distinct homozygous inbred lines that are then crossed in controlled manner. This segmentation allows maintaining uniformity within each line while achieving desired genetic diversity through specific crosses between lines.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent changes the genetic parameter from heterogeneous natural populations to homozygous inbred lines with fixed genetic composition. This parameter change enables uniformity within lines while allowing controlled diversity through crosses.

Inventive Principle:
Principle #35Parameter changes

2Stability of the object's composition

If self-pollination is used to create uniform inbred lines, then uniformity improves, but genetic diversity deteriorates

Engineering Contradiction:
ImproveuniformityVSAvoidgenetic diversity
Core Design Contradiction:
Stability of the object's compositionVSAdaptability or versatility

Solution Approach 1:

The patent applies preliminary self-pollination actions over multiple generations to create homozygous inbred lines before performing the actual crossing. This preliminary action establishes the uniform genetic foundation needed for predictable hybrid performance.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The breeding program maintains continuous self-pollination across multiple generations to progressively increase homozygosity and uniformity. This continuous action ensures complete genetic fixation before the crossing stage.

Inventive Principle:
Principle #20Continuity of useful action

3Adaptability or versatility

If non-uniform hybrid populations are produced, then genetic variability improves, but predictability deteriorates

Engineering Contradiction:
Improvegenetic variabilityVSAvoidpredictability
Core Design Contradiction:
Adaptability or versatilityVSReliability

Solution Approach 1:

The patent applies different genetic qualities to different parts of the breeding system: homozygous uniform lines for parental stock, and heterozygous variable hybrids for production. This local differentiation resolves the contradiction between variability and predictability.

Inventive Principle:
Principle #3Local quality

Solution Approach 2:

The homozygous inbred lines serve as intermediaries between the uniform parental generation and the variable hybrid generation. These standardized intermediaries enable predictable outcomes in hybrid production while maintaining genetic variability.

Inventive Principle:
Principle #24Intermediary (Mediator)

Data Source

PatentUS12628773B2Plants and seeds of corn variety CV622763
Publication Date: 2026.05.19 MONSANTO TECHNOLOGY LLC

AI summary

According to the disclosure, there is provided seed and plants of the corn variety designated CV622763. The disclosure thus relates to the plants, seeds, and tissue cultures of the variety CV622763, and to methods for producing a corn plant produced by crossing a corn plant of variety CV622763 with itself or with another corn plant, such as a plant of another variety. The disclosure further relates to corn seeds and plants produced by crossing plants of variety CV622763 with plants of another variety, such as another inbred line. The disclosure further relates to the inbred and hybrid genetic complements of plants of variety CV622763.