Corneal Flap Cutting Patterns for Bubble Management

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Solution Overview

Problem

Femtosecond lasers used in LASIK surgeries often create excessive gas bubbles during flap cutting in the corneal stroma, leading to tissue bridges and rough bed surfaces, which interfere with the cutting process and complicate flap lift.

Innovation Solution

Implementing a method using a resonant scanning femtosecond laser with specific flap cutting patterns that include intrastromal pockets to vent gas bubbles posterior and outside the flap bed and side cuts, ensuring complete tissue separation and minimizing tissue tags and opaque bubble layers.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If conventional flap cutting patterns are used, then the cutting process is simple, but gas bubbles create tissue bridges and rough bed surfaces that interfere with cutting

Engineering Contradiction:
Improvecutting qualityVSAvoidcutting pattern complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The flap cutting pattern is divided into multiple distinct components: a bed cut region, a peripheral ring cut, and multiple side cut layers at different depths. This segmentation allows each region to be optimized independently, with the ring cut specifically designed to intercept and vent gas bubbles before they can interfere with the bed cut, thereby improving cutting quality without requiring a completely complex redesign

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The invention introduces multiple side cut layers at different depths (Z-dimension) to address the gas bubble problem. By creating side cuts at multiple depth levels rather than a single plane, the design provides additional pathways for gas bubble venting and prevents tissue bridges from forming, improving reliability while adding controlled complexity in the depth dimension

Inventive Principle:
Principle #17Another dimension (Dimensionality change)

2Manufacturing precision

If laser scanning continues through bubble regions, then complete flap cutting is attempted, but bubbles block the laser beam creating uncut tissue regions

Engineering Contradiction:
Improveflap bed completenessVSAvoidcutting efficiency
Core Design Contradiction:
Manufacturing precisionVSProductivity

Solution Approach 1:

The peripheral ring cut is performed before the bed cut in a specific sequence. This preliminary ring cut creates a venting pathway that allows gas bubbles to escape before they can block the subsequent bed cut laser scanning. This preliminary action prevents bubble-induced interruptions and ensures complete flap cutting without reducing overall productivity

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The ring cut acts as an intermediary structure between the external environment and the bed cut region. It provides a dedicated pathway for gas bubbles to escape to the surface, mediating the interaction between laser scanning and gas bubbles. This intermediary structure prevents bubbles from directly blocking the bed cut laser beam, ensuring manufacturing precision while maintaining cutting efficiency

Inventive Principle:
Principle #24Intermediary (Mediator)

3Reliability

If single-layer side cuts are used, then the cutting process is faster, but gas bubbles accumulate and create opaque layers affecting cutting quality

Engineering Contradiction:
Improvebubble managementVSAvoidcutting time
Core Design Contradiction:
ReliabilityVSLoss of time

Solution Approach 1:

The side cut is segmented into multiple layers at different depths rather than a single continuous layer. This segmentation creates multiple venting pathways for gas bubbles at different depth levels, improving bubble management and cutting quality. The segmented approach, while adding some complexity, maintains reasonable cutting time by processing each layer efficiently

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

Different regions of the side cut are created with different local qualities - multiple discrete layers at different depths rather than a uniform single layer. This local quality variation provides targeted bubble venting pathways where needed, improving reliability without requiring a complete redesign of the entire cutting process, thus minimizing time loss

Inventive Principle:
Principle #3Local quality

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This approach improves the ease of flap lift and reduces the likelihood of tissue bridges and opaque bubble layers, enhancing the precision and efficiency of the LASIK flap cutting procedure.

Implementation Method 1

Femtosecond lasers are used to cut flaps in the corneal stroma as the first step of LASIK (laser-assisted in situ keratomileusis) surgeries

Methodology Applied
Scientific EffectPhotodisruption: Laser Ablation

Implementation Method 2

the interaction of the laser pulses with the tissue can sometimes create excessive gas bubbles which can interfere with the continued cutting of the tissue

Methodology Applied
Scientific EffectPhotodisruption: Laser Ablation

Data Source

PatentEP4389087A1Lasik corneal flap cutting patterns for bubble management
Publication Date: 2024.06.26 AMO DEVELOPMENT LLC
  • EP4389087A1 patent drawingFigure 1A~1D
  • EP4389087A1 patent drawingFigure 1E~2
  • EP4389087A1 patent drawingFigure 3A~3C

AI summary

An ophthalmic surgical laser system that employs a resonant scanner, scan line rotator, and XY- and Z-scanners, the system configured for forming a corneal flap in a patient's eye with improved bubble management during each step of the flap creation process. A pocket cut is formed first below bed level, followed by the bed connected to the pocket cut, then by a side cut extending from the bed to the anterior corneal surface. The pocket cut includes a pocket region located below the bed level and a ramp region connecting the pocket region to the bed. The bed is formed by a bed cut, including multiple overlapping parallel raster scan passes, and a ring cut. The side cut is formed by multiple side-cut layers at different depths which are joined together. All cuts are formed by scanning a laser scan line generated by the resonant scanner.