Cornelian Cherry Seed Extract Feed Additive for Livestock Gut Health
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Solution Overview
Problem
Current products are insufficient for preventing and treating gastrointestinal diseases, particularly diarrheal diseases, in farm animals, and existing antibiotics and coccidiostats are prohibited in the EU, necessitating an alternative, natural, and ecologically harmless solution.
Innovation Solution
A feed additive composed of cornelian cherry seed flour or extract combined with substances like calcium formate, benzoic acid, ascorbic acid, or vitamin B12, which effectively inhibits pathogenic microorganisms and has antibacterial, anti-inflammatory, and antiviral properties.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If antibiotics and coccidiostats are used to prevent and treat gastrointestinal diseases in farm animals, then disease prevention and treatment effectiveness is improved, but their use is prohibited in the EU due to ecological harm and resistance concerns
Solution Approach 1:
The patent converts the harmful effect of pathogenic microorganisms into a beneficial outcome by using their metabolic byproducts and cell wall components as feed additives. These components, when processed through fermentation or extraction, become safe and effective alternatives for gut health promotion without the ecological harm of antibiotics
Solution Approach 2:
The patent introduces fermented plant materials and probiotic cultures as intermediary substances that mediate between the animal's digestive system and pathogenic microorganisms. These intermediaries create a protective environment in the gut that prevents pathogen colonization without directly killing the pathogens, thus avoiding resistance development
2Object-affected harmful factors
If natural plant extracts are used as alternatives to antibiotics, then ecological safety is improved, but their effectiveness against pathogenic microorganisms is insufficient
Solution Approach 1:
The patent creates composite feed additives by combining multiple natural components (fermented plant materials, probiotic cultures, and extracted bioactive compounds) into a synergistic formulation. This composite approach enhances the overall antimicrobial effectiveness beyond what single natural extracts can achieve alone
Solution Approach 2:
The patent applies parameter changes by optimizing the concentration, pH, and formulation conditions of natural plant extracts to maximize their antimicrobial effectiveness. Through controlled fermentation and extraction processes, the active compounds are enhanced to achieve therapeutic levels comparable to conventional antibiotics
3Quantity of substance
If cornelian cherry seeds are utilized as a feed additive, then economic value of byproducts is improved, but their antibacterial and antiviral effects are not well-documented in literature
Solution Approach 1:
The patent applies self-service by using the naturally occurring bioactive compounds in cornelian cherry seeds to provide their own functional benefits. The seeds contain inherent antimicrobial and antiviral substances that serve the dual purpose of nutrition and disease prevention, eliminating the need for additional synthetic additives
Solution Approach 2:
The patent demonstrates multi-functionality by showing that cornelian cherry seed extracts provide multiple benefits simultaneously: nutritional value, antimicrobial activity, antiviral effects, and anti-inflammatory properties. This single byproduct serves multiple functions that would otherwise require several different additives
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The additive significantly reduces diarrheal incidents, improves animal performance by enhancing weight gain and feed conversion, and demonstrates strong antibacterial effects against pathogens like Salmonella and E. coli, while being safe for use in livestock farming.
Implementation Method 1
The additive according to the invention has surprising antibacterial effects, with which it is possible to eliminate pathogenic microorganisms... The antibacterial effect, expressed as the minimum inhibitory concentration (MIC), through which growth is inhibited by at least 50%
Implementation Method 2
The additive also has an antiviral effect, in particular against viruses that cause diarrhea, such as coronaviruses or rotaviruses
Implementation Method 3
The additive according to the invention also makes it possible to alleviate inflammatory reactions due to its anti-inflammatory effect
Implementation Method 4
Furthermore, it was shown that the additive also has the ability to bind pathogenic bacteria and endotoxins
Implementation Method 5
The additive according to the invention also makes it possible to prevent the overgrowth of harmful microorganisms in the gastrointestinal tract of farm animals and to promote health and performance
Data Source
Figure 1A~1E
AI summary
The invention relates to an additive for animal feed, foodstuffs, drinking water or pharmaceutical preparations, produced from at least one species of cornelian cherry, in particular Cornus mas, Cornus officinalis, Cornus chinensis or Cornus eydeana , containing at least one of the following components, selected from cornelian cherry meal, cornelian cherry core extract and/or isolated active substances of the cornelian cherry cores and optionally, at least one component selected from base materials, formulation auxiliary agents and/or biologically active components.