Learning-Based Shape Model for Coronary Artery CTA Analysis

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Solution Overview

Problem

Manual analysis of coronary artery computed tomography angiography (CTA) images is time-consuming and lacks high accuracy in diagnosing and treating coronary artery diseases.

Innovation Solution

A method and apparatus for modeling coronary artery structures using a learning-based shape model, which involves forming a shape model from landmark positions in 3D images, acquiring point positions and centerlines from target images, and segmenting the lumen using region-growing or graph-cut schemes, to assist in diagnosis and treatment.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If manual analysis of coronary artery CTA images is performed, then diagnostic accuracy can be achieved, but analysis time becomes excessively long

Engineering Contradiction:
Improvediagnostic accuracyVSAvoidanalysis time
Core Design Contradiction:
Measurement precisionVSLoss of time

Solution Approach 1:

The patent creates a learned shape model that copies and generalizes from manually annotated landmark positions in training images. This model can then automatically reproduce coronary artery structures in new images without requiring manual annotation for each case, thus maintaining diagnostic accuracy while dramatically reducing analysis time.

Inventive Principle:
Principle #26Copying

Solution Approach 2:

The patent performs preliminary action by training the shape model on a dataset of manually annotated images before actual diagnosis. The model learns the characteristic patterns and landmark positions during training, enabling it to automatically perform analysis on new patient images without requiring manual intervention during the diagnostic process.

Inventive Principle:
Principle #10Preliminary action

2Measurement precision

If manual analysis of coronary artery CTA images is performed, then diagnostic accuracy can be achieved, but the process becomes time-consuming

Engineering Contradiction:
Improvediagnostic accuracyVSAvoidanalysis efficiency
Core Design Contradiction:
Measurement precisionVSProductivity

Solution Approach 1:

The learned shape model copies the successful manual annotation process by internally storing the patterns and relationships learned from training data. When applied to new images, the model reproduces accurate coronary artery segmentations and landmark positions automatically, maintaining diagnostic accuracy while improving productivity by eliminating repetitive manual work.

Inventive Principle:
Principle #26Copying

Solution Approach 2:

The patent replaces the mechanical manual annotation process with an automated neural network-based system. The model substitutes human expertise with a computational system that can process images rapidly, maintaining the diagnostic accuracy achieved through manual analysis while dramatically improving analysis efficiency and productivity.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

3Loss of time

If a learning-based shape model is used to automate coronary artery modeling, then analysis time is reduced, but model complexity increases

Engineering Contradiction:
Improveanalysis timeVSAvoidmodel complexity
Core Design Contradiction:
Loss of timeVSDevice complexity

Solution Approach 1:

The patent segments the complex task of coronary artery analysis into distinct components: training phase (where the model learns from annotated data) and inference phase (where the model automatically analyzes new images). This segmentation allows the complex learning process to be encapsulated in the trained model, reducing the complexity burden during actual diagnostic use while maintaining time efficiency.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The learned shape model copies the complex patterns and relationships from training data into a compressed representation. During inference, the model simply needs to match these pre-learned patterns against new images, which is computationally much lighter than performing manual analysis. This copying approach reduces operational complexity while maintaining the accuracy achieved through extensive training.

Inventive Principle:
Principle #26Copying

Data Source

PatentUS9990729B2Methods of and apparatuses for modeling structures of coronary arteries from three-dimensional (3D) computed tomography angiography (CTA) images
Publication Date: 2018.06.05 SAMSUNG ELECTRONICS CO LTD
  • US9990729B2 patent drawing
  • US9990729B2 patent drawing
  • US9990729B2 patent drawing

AI summary

A method of modeling a structure of a coronary artery of a subject may include: forming a learning-based shape model of the structure of the artery, based on positions of landmarks acquired from three-dimensional images; receiving a target image; and/or modeling the artery structure included in the target image, using the model. An apparatus for modeling a structure of a coronary artery may include: a memory configured to store a learning-based shape model of the artery, the learning-based shape model being formed based on positions of a plurality of landmarks acquired from three-dimensional images, the plurality of the landmarks corresponding to the artery; a communication circuit configured to receive a target image; and/or a processing circuit configured to model the artery structure included in the target image, using the model.