3D Coronary Modeling for Rapid Post-PCI Flow Assessment
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Solution Overview
Problem
Existing methods for assessing the effectiveness of percutaneous coronary intervention (PCI) are time-consuming and inflexible, failing to provide immediate insights into the long-term success of PCI treatments.
Innovation Solution
A system and method using non-invasive techniques to analyze post-PCI images and diagnostic images, generating a three-dimensional model to determine vascular function indices like fractional flow reserve (FFR), allowing for real-time assessment of PCI effectiveness by comparing pre- and post-PCI images.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Measurement precision
If traditional methods for assessing PCI effectiveness are used, then comprehensive vascular analysis can be performed, but the assessment process is time-consuming and does not provide immediate insights
Solution Approach 1:
The system performs preliminary processing of angiographic images to generate a three-dimensional model of the coronary vasculature before the PCI procedure. This pre-established model framework allows for rapid post-PCI assessment by simply updating the model with post-procedure images rather than performing complete re-analysis, thus providing immediate insights while maintaining comprehensive vascular analysis accuracy
Solution Approach 2:
The system creates a digital three-dimensional copy of the coronary vasculature that can be repeatedly updated and analyzed without requiring repeated invasive imaging procedures. This virtual model serves as a persistent representation that enables rapid comparison between pre- and post-PCI states, eliminating time-consuming repeated physical assessments while maintaining measurement precision
2Measurement precision
If detailed vascular modeling is performed to ensure accurate PCI assessment, then measurement precision is improved, but the system complexity increases
Solution Approach 1:
The vascular assessment system divides the coronary vasculature into distinct segments and focuses analysis on specific regions of interest affected by PCI. This segmentation allows the complex three-dimensional model to be managed in manageable portions, reducing computational complexity while maintaining precision in the treated areas through targeted analysis rather than whole-system re-evaluation
3Object-affected harmful factors
If non-invasive techniques are used for post-PCI assessment, then patient safety is improved by avoiding additional invasive procedures, but the ability to obtain detailed internal vascular data may be reduced
Solution Approach 1:
The system uses angiographic images as an intermediary medium that captures sufficient vascular information non-invasively. These images serve as a bridge between the external imaging modality and the internal three-dimensional vascular model, allowing detailed internal vascular data to be reconstructed and analyzed without requiring additional invasive procedures. The intermediary imaging data is processed through image processing algorithms that extract comprehensive vascular characteristics while keeping patients out of harm's way
Data Source
AI summary
Systems and methods for post-PCI coronary analysis. An example method includes accessing a plurality of angiographic images depicting at least one vessel of a patient's heart, the angiographic images including two or more post-percutaneous coronary intervention (post-PCI) images and one or more diagnostic images, wherein the post-PCI images depict a PCI location in which a PCI is included to revascularize a lesion, and wherein the diagnostic images depict the lesion; receiving, via a user interface presenting the post-PCI images, user input specifying positions of the PCI location in the post-PCI images; determining an index indicative of vascular function based on the angiographic images, wherein the index is derived based on a three-dimensional model of the portion of the patient's heart, and wherein individual portions of the diagnostic images depicting the lesion are masked during generation of three-dimensional model; and presenting, via the user interface, summary information associated with PCI, the summary information including at least the determined index.