Multiphase Coronary Vessel Map Generation via CTA and 3DRA Integration
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Solution Overview
Problem
Current medical imaging techniques for coronary vessels are limited by the inability to visualize occluded segments, as cardiac computed tomography angiography (CTA) is typically performed at diastole, providing only a single-phase map, which restricts applications like three-dimensional cardiac road-mapping for chronic total occlusions (CTO) treatments.
Innovation Solution
A device and method that combine computed tomography angiography (CTA) and three-dimensional rotational angiography (3DRA) data to generate a complete multiphase map of coronary vessels by extracting a first vessel map from CTA data at a reference cardiac phase, interpolating and merging it with 3DRA data at various phases to reveal occluded segments, using a data extracting, interpolation, and merging module.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Loss of information
If cardiac CTA is performed at diastole to obtain a complete coronary map, then the occluded vessel segments are visible, but only a single-phase map is available which is insufficient for three-dimensional cardiac road-mapping in CTO treatments
Solution Approach 1:
The CTA examination is performed in advance to obtain a complete coronary map including occluded segments. This preliminary data is then integrated with 3DRA data acquired during the intervention to create multiphase maps, allowing the complete anatomical information to be available before the procedure begins.
Solution Approach 2:
The patent combines CTA data (which shows occluded segments) with 3DRA data (which provides multiphase information) through registration and merging processes. This integration creates composite multiphase maps that contain both the complete anatomical information from CTA and the temporal information from 3DRA.
2Loss of information
If CTA and 3DRA data are combined to create multiphase maps, then complete coronary visualization is achieved, but the complexity of data processing and integration increases
Solution Approach 1:
The patent uses 3DRA data as an intermediary to bridge the gap between CTA and the final multiphase maps. The 3DRA data serves as a mediator that connects the anatomical information from CTA with the temporal requirements for road-mapping, simplifying the integration process through sequential registration and merging steps.
Solution Approach 2:
The data processing is divided into distinct segments: first extracting coronary maps from CTA data, then registering 3DRA data at different phases, and finally merging these datasets. This segmentation of the processing workflow manages complexity by breaking down the integration task into manageable, sequential operations.
Data Source
AI summary
A device for medical imaging of coronary vessels includes a data extracting module configured to extract a first vessel map from computed tomography angiography data covering at least one reference cardiac phase and a set of second vessel maps from three-dimensional rotational angiography data covering at least one cardiac cycle. An interpolation module is configured to generate a series of warped versions of the first vessel map aligned with the set of second vessel maps, the series starting at the at least one reference cardiac phase. A merging module is configured to merge the series and the set of second vessel maps at the different phases in order to generate a final imaging map of the coronary vessels.