Blood Glucose Correction Factor Determination Using Insulin Bolus Data
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Solution Overview
Problem
Conventional insulin therapy methods, such as multiple daily injections, are inconvenient and limited in controlling blood glucose levels, as they require frequent tracking of insulin doses and blood glucose measurements, and often result in variations in blood glucose levels, potentially leading to complications like high or low blood sugar.
Innovation Solution
A blood glucose management device with a user interface, input, and controller that determines an effective correction factor by analyzing sampled blood glucose data after an initial insulin correction bolus, allowing for precise adjustment of insulin dosages to maintain target blood glucose levels, thereby reducing the risk of complications.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If multiple daily injections (MDI) are used to manage blood glucose levels, then blood glucose control is improved, but the convenience and ease of operation deteriorates due to frequent tracking of insulin doses and blood glucose measurements
Solution Approach 1:
The system automatically determines correction factors by analyzing blood glucose data without requiring manual intervention. The processor automatically receives blood glucose data from the glucose monitor, calculates the correction factor based on the relationship between insulin dosage and blood glucose change, and updates the insulin pump settings, enabling the system to self-adjust and self-optimize therapy parameters
Solution Approach 2:
The system implements a closed-loop feedback mechanism where blood glucose measurements are continuously monitored, compared against target ranges, and used to automatically adjust insulin delivery parameters. The correction factor determination process uses feedback from actual blood glucose responses to insulin injections to refine future insulin dosing decisions
2Ease of operation
If conventional insulin therapy with one or two injections per day is used, then the ease of operation is improved, but the reliability of blood glucose control deteriorates due to larger variations in blood glucose levels
Solution Approach 1:
The system dynamically adjusts insulin therapy parameters based on real-time blood glucose data and individual patient responses. The correction factor is not fixed but is continuously determined and updated based on actual physiological responses, allowing the therapy to adapt to changing conditions and optimize control without requiring frequent manual adjustments by the patient
3Measurement precision
If frequent blood glucose testing is performed to determine correction factors, then the precision of correction factor determination is improved, but the loss of time and patient burden increases
Solution Approach 1:
The system performs preliminary determination of correction factors during routine blood glucose monitoring activities. By analyzing blood glucose data that would be collected anyway for routine management, the system determines correction factors without requiring additional separate testing sessions, thus obtaining precise measurements without extra time burden
Data Source
AI summary
An apparatus comprises receiving a user prompt in a blood glucose (BG) management device to start a determination of an effective correction factor, receiving sampled blood glucose data of a patient obtained during a specified time duration, including a time duration after delivery of an initial insulin correction bolus, determining the effective correction factor using the BG management device according to a determined decrease in the blood glucose level of the patient and an amount of insulin in the initial insulin correction bolus, and cancelling the determination of the effective correction factor if a blood glucose level of the patient is outside of a specified range of blood glucose levels.