Cotton Variety 11PCLY50 Cytoplasmic Male Sterility Breeding

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Solution Overview

Problem

Existing cotton breeding techniques face challenges in developing cotton varieties with broad adaptation, excellent yield stability, and resistance to pests and diseases, while also maintaining high fiber quality and herbicide tolerance.

Innovation Solution

The development of a novel cotton inbred variety, 11PCLY50, which possesses broad adaptation, excellent yield stability, and incorporates transgenic events for resistance to Lepidoptera insects and tolerance to various herbicides, along with improved fiber properties.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If traditional self-pollination and sib-pollination techniques are used for inbreeding, then new cotton varieties can be developed, but the vigor of the lines decreases and additional inbreeding merely serves to increase seed production

Engineering Contradiction:
Improveseed productionVSAvoidline vigor
Core Design Contradiction:
ProductivityVSReliability

Solution Approach 1:

The patent uses cytoplasmic male sterility (CMS) as an intermediary mechanism to control pollination. By introducing a sterile line with specific cytoplasm that prevents self-pollination, the system ensures cross-pollination occurs between different lines, maintaining vigor while producing hybrid seeds. The sterile line acts as a mediator that forces outcrossing without requiring manual emasculation.

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The patent changes the fertility parameter of the cotton plant by introducing cytoplasmic male sterility. This parameter change transforms the plant from capable of self-pollination to incapable of producing functional pollen, thereby ensuring cross-pollination. The sterility is later restored in the F1 hybrid through nuclear restorer genes, allowing the hybrid to maintain vigor while the parent lines remain sterile for seed production.

Inventive Principle:
Principle #35Parameter changes

2Reliability

If manual emasculation is performed to prevent self-pollination in hybrid seed production, then cross-pollination can be ensured, but the process complexity and labor requirements increase

Engineering Contradiction:
Improvecross-pollination controlVSAvoidbreeding process complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent employs cytoplasmic male sterility to make the plant self-regulate its pollination behavior. The sterile cytoplasm automatically prevents pollen production and self-pollination without requiring external intervention or manual emasculation. The plant essentially services itself by being inherently incapable of self-fertilization, thereby ensuring cross-pollination occurs naturally.

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The CMS cytoplasm acts as an intermediary that mediates the pollination process. Instead of requiring manual removal of stamens, the cytoplasmic factor intervenes to prevent pollen development, thereby controlling cross-pollination automatically. This intermediary mechanism replaces complex manual procedures with a biological control system.

Inventive Principle:
Principle #24Intermediary (Mediator)

3Adaptability or versatility

If cotton plants are bred for broad adaptation and yield stability, then the variety can be grown in different production areas, but the fiber quality and pest resistance may be compromised

Engineering Contradiction:
Improveproduction area adaptationVSAvoidfiber quality
Core Design Contradiction:
Adaptability or versatilityVSManufacturing precision

Solution Approach 1:

The patent merges multiple desirable traits from different parent lines into a single F1 hybrid. By crossing a line with broad adaptation and yield stability with another line possessing superior fiber quality and pest resistance, the hybrid combines all these traits simultaneously. The merging of parental genomes allows the offspring to express a composite of beneficial characteristics that neither parent possesses alone.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The F1 hybrid represents a composite genetic material combining DNA from both parents. This genetic composite integrates alleles for broad adaptation, yield stability, fiber quality, and pest resistance into a unified genome. The hybrid's composite genetic constitution allows it to exhibit a suite of traits that exceed the performance of individual parent lines across multiple parameters.

Inventive Principle:
Principle #40Composite materials

4Stability of the object's composition

If inbreeding is practiced for multiple generations to develop homozygous varieties, then uniformity is enhanced, but the vigor of the lines decreases significantly

Engineering Contradiction:
Improvegenetic uniformityVSAvoidplant vigor
Core Design Contradiction:
Stability of the object's compositionVSReliability

Solution Approach 1:

The patent inverts the traditional approach by using cytoplasmic male sterility to prevent inbreeding rather than promoting it. Instead of practicing multiple generations of self-pollination to achieve homozygosity, the system uses CMS to force continuous outcrossing. The inversion lies in using sterility (normally a negative trait) as a tool to maintain vigor while achieving the desired uniformity through controlled hybridization rather than inbreeding.

Inventive Principle:
Principle #13The other way round (Inversion)

Solution Approach 2:

The patent performs preliminary action by establishing cytoplasmic male sterility in the parent lines before hybridization. This preliminary introduction of sterility prevents subsequent self-pollination and inbreeding depression. By pre-configuring the genetic system to enforce cross-pollination, the method avoids the vigor loss that would otherwise occur with continued inbreeding while maintaining genetic uniformity through consistent hybrid production.

Inventive Principle:
Principle #10Preliminary action

Data Source

PatentUS12207619B2Cotton variety 11PCLY50
Publication Date: 2025.01.28 PIONEER HI BREED INTERNATIONAL INC

AI summary

The disclosure relates to a cotton variety, designated 11PCLY50, the plants and seeds of the cotton variety 11PCLY50, methods for producing a cotton plant, either varietal or hybrid, produced by crossing the cotton variety 11PCLY50 with itself or with another cotton plant, hybrid cotton seeds and plants produced by crossing the variety 11PCLY50 with another cotton variety or plan, methods for producing a cotton plant containing in its genetic material one or more transgenes, and the transgenic cotton plants produced by that method. This disclosure also relates to cotton varieties derived from cotton variety 11PCLY50, to methods for producing other cotton varieties derived from cotton variety 11PCLY50, and to the varieties derived by the use of those methods.