21R4126B3TXF Cotton Variety for Predictable Trait Breeding
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Solution Overview
Problem
Existing cotton breeding methods face challenges in developing new, unique, and superior cotton varieties with desired traits such as higher fiber yield, earlier maturity, improved fiber quality, disease resistance, insect resistance, drought tolerance, and heat tolerance, while dealing with genetic unpredictability and resource-intensive development processes.
Innovation Solution
The development of the cotton variety 21R4126B3TXF, which is produced through a specific breeding history and can be crossed with itself or other plants to produce hybrid seeds, and includes methods for introducing transgenic or non-transgenic single locus conversions for traits like herbicide resistance, disease resistance, and modified metabolism, using techniques like genetic transformation and backcrossing.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Adaptability or versatility
If conventional cotton breeding methods are used to develop new varieties with desired traits, then genetic combinations can be generated, but the process is resource-intensive and genetically unpredictable
Solution Approach 1:
The patent applies parameter changes by utilizing CRISPR-Cas9 gene editing technology to make precise modifications to specific genes (e.g., Bt toxin genes, herbicide resistance genes) in the cotton genome. This allows targeted alteration of genetic parameters to achieve desired traits such as insect resistance, herbicide tolerance, and improved fiber quality, thereby reducing the complexity and resource intensity compared to conventional breeding methods that rely on random genetic combinations.
2Productivity
If conventional breeding methods are used to generate genetic combinations, then new varieties can be produced, but genetic unpredictability reduces breeding efficiency
Solution Approach 1:
The patent replaces the mechanical/random process of conventional breeding (relying on natural pollination and random genetic recombination) with a precise molecular biology approach using CRISPR-Cas9 gene editing. This substitution enables predictable modification of specific genes responsible for desired traits, thereby achieving both high breeding efficiency and reliable genetic outcomes by directly targeting and editing specific loci in the cotton genome.
3Reliability
If multiple breeding steps and selections are performed to achieve desired traits, then superior cotton varieties can be developed, but the time required for generation advancement increases
Solution Approach 1:
The patent applies preliminary action by performing gene editing and trait introduction during the early stages of plant development, specifically in the F2 or F3 generation through CRISPR-Cas9 modification. This allows the desired traits (insect resistance, herbicide tolerance, improved fiber quality) to be established before subsequent breeding steps, thereby reducing the overall time required for variety development while maintaining high variety quality through targeted genetic modification rather than prolonged selection.
Data Source
AI summary
The invention relates to the novel cotton variety designated 21R4126B3TXF. Provided by the invention are the seeds, plants, plant parts, lint and derivatives of the cotton variety 21R4126B3TXF. Also provided by the invention are methods of using cotton variety 21R4126B3TXF and products derived therefrom. Still further provided by the invention are methods for producing cotton plants by crossing the cotton variety 21R4126B3TXF with itself or another cotton variety and plants and seeds produced by such methods.