Cardiopulmonary Blood Volume Monitoring via Arterial Pulse Pressure Analysis

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Solution Overview

Problem

Current methods for determining cardiopulmonary blood volume are discontinuous, labor-intensive, and costly, requiring user interaction and not providing real-time data.

Innovation Solution

An apparatus and computer program utilize physiological heart-lung interaction during spontaneous breathing or mechanical ventilation to continuously and automatically calculate cardiopulmonary blood volume by analyzing the envelope of arterial pulse pressure, allowing for continuous and cost-effective determination.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If indicator dilution techniques are used to determine cardiopulmonary blood volume, then measurement precision is improved, but productivity deteriorates due to discontinuous and labor-intensive determination

Engineering Contradiction:

Improvecardiopulmonary blood volume measurement precisionVSAvoiddetermination speed

Core Design Contradiction:

Measurement precisionVSProductivity

Solution Approach 1:

The system automatically performs cardiopulmonary blood volume determination without requiring user interaction. The control unit automatically processes arterial pulse pressure signals, calculates transit times, and determines CPBV values continuously, eliminating the need for manual intervention in each measurement cycle.

Inventive Principle:

Principle #25Self-service

Solution Approach 2:

The system enables continuous determination of cardiopulmonary blood volume by continuously analyzing arterial pulse pressure signals. Unlike discrete indicator dilution methods, this approach provides ongoing real-time monitoring of CPBV changes without interruption or manual re-initialization.

Inventive Principle:

Principle #20Continuity of useful action

2Measurement precision

If indicator dilution techniques are used to determine cardiopulmonary blood volume, then measurement precision is improved, but device complexity increases due to requirement of indicator injection and concentration measurement

Engineering Contradiction:

Improvecardiopulmonary blood volume measurement precisionVSAvoidmeasurement system complexity

Core Design Contradiction:

Measurement precisionVSDevice complexity

Solution Approach 1:

The system extracts the measurement function from complex indicator injection and concentration detection equipment. By using arterial pulse pressure analysis, the method eliminates the need for indicator injection systems, concentration sensors, and associated complex measurement apparatus while maintaining measurement capability.

Inventive Principle:

Principle #2Taking out (Extraction)

Solution Approach 2:

The system replaces the mechanical and chemical indicator dilution method with a physiological signal analysis approach. Instead of injecting indicators and measuring concentration changes, the system uses electrical/pressure signal processing of arterial pulse pressure to derive transit time and CPBV information.

Inventive Principle:

Principle #28Mechanics substitution (Replace mechanical system)

3Measurement precision

If indicator dilution techniques are used to determine cardiopulmonary blood volume, then measurement precision is improved, but loss of time increases due to discontinuous determination

Engineering Contradiction:

Improvecardiopulmonary blood volume measurement precisionVSAvoidtime between measurements

Core Design Contradiction:

Measurement precisionVSLoss of time

Solution Approach 1:

Inventive Principle:

Principle #20Continuity of useful action

4Productivity

If arterial pulse pressure analysis is used to determine cardiopulmonary blood volume, then productivity is improved through continuous automatic determination, but measurement precision may deteriorate

Engineering Contradiction:

Improvedetermination speedVSAvoidcardiopulmonary blood volume measurement precision

Core Design Contradiction:

ProductivityVSMeasurement precision

Solution Approach 1:

The system uses feedback from arterial pulse pressure waveform analysis to continuously monitor and adjust measurements. By analyzing the envelope characteristics and transit time variations in the pulse pressure signal, the system maintains measurement accuracy while enabling continuous automatic determination.

Inventive Principle:

Principle #23Feedback

Solution Approach 2:

The system dynamically adapts to changing physiological conditions by continuously analyzing arterial pulse pressure signals. The measurement process adjusts to varying heart rates, blood pressure patterns, and respiratory influences, maintaining precision across different physiological states rather than requiring fixed measurement protocols.

Inventive Principle:

Principle #15Dynamics

Data Source

PatentEP1870035B1Apparatus and computer program for determining a patient's volemic status represented by cardiopulmonary blood volume

Publication Date: 2015.12.30 EDWARDS LIFESCIENCES IPRM AG

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AI summary

An apparatus for determining a patient's volemic status is adapted to make use of a physiological heart-lung interaction during spontaneous breathing or mechanical ventilation. Further, a computer program for determining the patient's volemic status has instructions adapted to carry out the steps of generating data of a physiological heart-lung interaction during spontaneous breathing or mechanical ventilation, and determining the patient's volemic status when making use of the data of the physiological heart-lung interaction, when run on a computer.