Cranberry Extract Normalizes Lipid Metabolism
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Solution Overview
Problem
Current methods fail to effectively normalize HDL/LDL cholesterol metabolism, leading to adverse health effects and lifestyle changes for individuals with high LDL or low HDL cholesterol levels, necessitating a non-medical solution for oral consumption.
Innovation Solution
A dietary supplement containing extracts from cranberry, blackberry, or agrimony plants, preferably from their leaves, is used for oral ingestion to normalize HDL/LDL cholesterol levels by increasing HDL and reducing LDL cholesterol in the blood plasma.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If lifestyle changes and diet adjustments are implemented to normalize lipid metabolism, then LDL cholesterol levels can be reduced and HDL cholesterol levels can be increased, but the subjective quality of life of affected individuals is negatively affected
Solution Approach 1:
The patent introduces plant extracts (cranberry, blackberry, or agrimony) as an intermediary substance that mediates between the patient and the lipid metabolism system. These extracts contain active compounds that directly interact with lipid metabolism pathways, enabling normalization of cholesterol levels without requiring extensive lifestyle changes or diet restrictions, thus preserving quality of life while achieving the therapeutic effect
2Reliability
If medication is used to normalize lipid metabolism, then LDL cholesterol levels are reduced and HDL cholesterol levels are increased, but the need for medication affects the patient's quality of life and may require long-term dependency
Solution Approach 1:
The patent employs plant-based extracts that can be administered as short-term or intermittent treatments rather than lifelong medication dependency. The extracts from cranberry, blackberry, or agrimony serve as temporary but effective interventions that normalize lipid metabolism parameters without creating long-term pharmacological dependency, allowing patients to discontinue treatment once normalization is achieved
3Ease of operation
If no intervention is taken for elevated LDL or low HDL cholesterol levels, then lifestyle and quality of life are preserved, but adverse health effects and increased risk of arteriosclerosis and heart attacks occur
Solution Approach 1:
The patent enables preliminary action by providing a preventive treatment option that can be taken before severe health complications develop. The plant extracts can be administered to individuals with elevated LDL or low HDL cholesterol levels to prevent the progression to arteriosclerosis and heart attacks, addressing the health risk early while maintaining quality of life through minimal lifestyle disruption
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The supplement effectively reduces LDL cholesterol and increases HDL cholesterol levels, achieving normal ranges and improving lipid metabolism, comparable to statin effects, with increased LDL receptor expression and cholesterol uptake.
Implementation Method 1
increased LDL receptor expression
Implementation Method 2
LDL cholesterol is removed from the blood through endocytosis and binding to LDL receptors (LDLR), primarily in the liver
Implementation Method 3
thereby simultaneously reducing intracellular cholesterol synthesis
Data Source
Figure 1a~1g
Figure 2a~3
Figure 4a~4e
AI summary
The invention relates to the field of dietary supplements. In particular, the invention relates to a non-medical method for normalizing lipid metabolism, especially HDL/LDL cholesterol metabolism, a product for oral administration, a dietary supplement, and the non-medical use of an extract from the cranberry plant and/or an extract from the blackberry plant for normalizing lipid metabolism.