Cranberry Seed Composition for Lower Urinary Tract Symptoms

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Solution Overview

Problem

Current treatments for lower urinary tract symptoms (LUTS), benign prostatic hyperplasia (BPH), erectile dysfunction (ED), urinary incontinence, and overactive bladder often come with significant side effects, necessitating the development of new, effective treatments.

Innovation Solution

A therapeutic composition comprising dried cranberry powder combined with dried cranberry seeds or cranberry seed meal, which provides a natural and effective solution for alleviating LUTS and associated conditions without the side effects of traditional treatments.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If registered pharmacological treatments are used for LUTS, then treatment effectiveness is improved, but side effects increase

Engineering Contradiction:

Improvetreatment effectivenessVSAvoidside effects

Core Design Contradiction:

ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent changes the chemical composition parameters by using plant-based compounds (beta-sitosterol, fatty acids, phospholipids, triterpenes) instead of conventional pharmaceutical agents, thereby maintaining treatment effectiveness while eliminating synthetic drug side effects

Inventive Principle:

Principle #35Parameter changes

Solution Approach 2:

The patent employs a composite approach by combining multiple cranberry-derived components (seeds, seed meal, powder) that contain synergistic mixtures of bioactive compounds, creating a multifaceted therapeutic formulation that addresses LUTS through multiple mechanisms simultaneously

Inventive Principle:

Principle #40Composite materials

2Reliability

If cranberry seeds and seed meal are added to dried cranberry powder, then therapeutic efficacy is improved, but manufacturing complexity increases

Engineering Contradiction:

Improvetherapeutic efficacyVSAvoidmanufacturing complexity

Core Design Contradiction:

ReliabilityVSDevice complexity

Solution Approach 1:

The patent segments the cranberry fruit into distinct components (seeds, seed meal, and powder) that are processed separately to preserve their unique bioactive properties, then combines them in a final formulation to achieve enhanced therapeutic efficacy

Inventive Principle:

Principle #1Segmentation

Solution Approach 2:

The patent creates a multi-functional composition where cranberry seeds provide specific phytochemicals, seed meal contributes additional bioactive compounds, and dried cranberry powder serves as both a therapeutic agent and a carrier matrix, allowing a single product to address multiple aspects of LUTS pathology

Inventive Principle:

Principle #6Universality (Multi-functionality)

Data Source

PatentUS12233101B2Compositions and methods useful in treatment of lower urinary tract symptoms, benign prostatic hyperplasia, erectile dysfunction, and other diseases or symptoms

Publication Date: 2025.02.25 NATUREX INC

AI summary

The invention relates to therapeutic compositions, solid oral dosage forms, and methods for treating, preventing, or alleviating lower urinary tract symptoms (LUTS), benign prostatic hyperplasia (BPH), erectile dysfunction (ED), urinary incontinence, bladder obstruction, overactive bladder (OAB), underactive bladder, interstitial cystitis, prostatitis, bladder and prostate inflammation, prostate fibrosis or pelvic pain. The therapeutic compositions can comprise cranberry powder enriched in cranberry seeds or cranberry seed meal.