Cross-Controlled Blood Circulation System for Heart Unloading

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Solution Overview

Problem

Current blood circulation systems face challenges in accurately controlling the flow rate of blood when using combination of percutaneous blood circulation devices and venoarterial extracorporeal membrane oxygenation, leading to increased burden on the heart and difficulty in adjusting flow rates according to patient conditions.

Innovation Solution

A blood circulation system that includes a first and second blood circulation device, each with a centrifugal pump and a detection unit, where the control section of one device controls the centrifugal pump based on the flow rate detection from the other device, allowing for precise adjustment of blood flow rates according to patient conditions.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Volume of moving object

If an axial flow pump is built in the catheter of the first blood circulation device, then the device can be miniaturized and inserted percutaneously, but the flow rate cannot be directly measured and accurately controlled

Engineering Contradiction:
Improvedevice sizeVSAvoidflow rate measurement accuracy
Core Design Contradiction:
Volume of moving objectVSMeasurement precision

Solution Approach 1:

The patent introduces a flow rate sensor as an intermediary measurement device placed in the blood circulation circuit to detect flow rate. This allows indirect measurement of the axial flow pump's performance without requiring direct integration of measurement capabilities into the pump itself, resolving the contradiction between device miniaturization and flow rate measurement accuracy.

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The patent replaces direct mechanical measurement of axial flow pump output with electronic sensing and signal processing systems. The flow rate sensor converts mechanical flow information into electrical signals that can be processed to determine flow rate, enabling accurate measurement despite the pump's integrated design.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

2Ease of operation

If the axial flow pump's unloading flow rate is calculated based on rotation speed and motor current, then the control system can operate, but the calculation is inaccurate due to sharp flow rate changes from pressure differences

Engineering Contradiction:
Improvecontrol system operationVSAvoidunloading flow rate calculation accuracy
Core Design Contradiction:
Ease of operationVSMeasurement precision

Solution Approach 1:

The patent implements a feedback control system where the flow rate sensor continuously monitors actual flow rate and provides this information back to the control unit. The control unit then adjusts the axial flow pump's rotation speed based on this feedback, compensating for the inaccuracies in calculating flow rate from rotation speed and motor current alone.

Inventive Principle:
Principle #23Feedback

Solution Approach 2:

The patent replaces indirect calculation of flow rate based on mechanical parameters (rotation speed, motor current) with direct electronic sensing. The flow rate sensor provides accurate real-time measurement of actual blood flow, substituting the unreliable mechanical calculation method with precise electronic detection.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

3Reliability

If both the first and second blood circulation devices are used in combination, then the burden on the patient's heart is reduced and survival rate is improved, but the difficulty in appropriately adjusting flow rates increases

Engineering Contradiction:
Improvepatient survival rateVSAvoidflow rate adjustment complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent merges the control systems of the first and second blood circulation devices into a coordinated operation. The control unit integrates information from both devices and the flow rate sensor to manage overall blood flow, simplifying the adjustment process despite having multiple devices operating simultaneously.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The patent implements a unified feedback control system that monitors total blood flow through the flow rate sensor and coordinates the operation of both blood circulation devices. This feedback mechanism allows the control unit to automatically adjust both devices' flow rates in a coordinated manner, reducing the complexity of manual adjustment while maintaining patient safety and improving outcomes.

Inventive Principle:
Principle #23Feedback

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Enables accurate control of blood flow rates through both devices, reducing the burden on the heart and improving patient survival rates by allowing for real-time adjustments based on changing patient conditions.

Implementation Method 1

A first centrifugal pump that is disposed outside the living body, includes a first inlet port and a first outlet port, removes blood from the left ventricle to the first inlet port via the first blood removal vessel portion, and sends blood from the first outlet port to the ascending aorta via the first blood sending vessel portion

Methodology Applied
Scientific EffectCentrifugal force: Centrifugal Force

Implementation Method 2

a detection unit that is disposed outside the living body and detects a flow rate of blood flowing through the second blood sending vessel portion

Methodology Applied
Scientific EffectFlow rate detection:

Data Source

PatentUS20240216669A1Blood circulation system
Publication Date: 2024.07.04 TERUMO KK
  • US20240216669A1 patent drawing
  • US20240216669A1 patent drawing
  • US20240216669A1 patent drawing

AI summary

In a blood circulation system (10), a first blood circulation device (12) includes a first detection unit (22) that detects a first flow rate of blood flowing through a first blood sending vessel portion (28). A second blood circulation device (14) includes a second detection unit (95) that detects a second flow rate of blood flowing through a blood sending cannula (110). A first control section (74) controls a first centrifugal pump (20) based on a detection result of the second detection unit (95). A second control section (154) controls a second centrifugal pump (92) based on a detection result of the first detection unit (22).