Cross-Modality Image Registration for Surgical Navigation Accuracy

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Solution Overview

Problem

Existing computer-assisted surgery navigation systems face challenges in registering pre-operative images from one imaging modality to intra-operative images of a different modality, particularly due to differences in imaging techniques like MRI and CT, which affect the accuracy of surgical instrument navigation.

Innovation Solution

The method involves transforming pre-operative images from one imaging modality to an estimate in another modality using neural networks, registering these estimates to intra-operative navigable images, and utilizing camera tracking systems for precise surgical navigation.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Device complexity

If pre-operative images from one imaging modality (e.g., MRI) are directly registered to intra-operative images of a different modality (e.g., CT), then the registration process is simplified, but the accuracy of surgical instrument navigation deteriorates due to differences in imaging techniques

Engineering Contradiction:
Improveregistration process complexityVSAvoidsurgical instrument navigation accuracy
Core Design Contradiction:
Device complexityVSMeasurement precision

Solution Approach 1:

The patent introduces a third imaging modality as an intermediary reference frame. Pre-operative images from the first modality are transformed into the third modality, and intra-operative images from the second modality are also transformed into the third modality. This intermediary transformation enables accurate cross-modality registration by providing a common reference space, resolving the contradiction between simplified registration and navigation accuracy.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Measurement precision

If multiple imaging modalities are acquired and transformed to a common reference frame, then the accuracy of image alignment is improved, but the radiation exposure and cost increase

Engineering Contradiction:
Improveimage alignment accuracyVSAvoidradiation exposure
Core Design Contradiction:
Measurement precisionVSObject-affected harmful factors

Solution Approach 1:

The patent performs the transformation of pre-operative images to the third imaging modality before the surgical procedure begins. This preliminary transformation allows the system to use the transformed pre-operative images throughout the surgery without requiring additional intra-operative scanning, thereby reducing radiation exposure while maintaining alignment accuracy.

Inventive Principle:
Principle #10Preliminary action

3Measurement precision

If real-time tracking of surgical instruments is implemented using camera tracking systems, then the precision of surgical navigation is improved, but the system complexity and computational requirements increase

Engineering Contradiction:
Improvesurgical navigation precisionVSAvoidsystem complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent creates a virtual copy of the patient's anatomy in the third imaging modality that serves as a reference framework. The camera tracking system then tracks the position of surgical instruments relative to this virtual model, rather than requiring complex direct registration between multiple real imaging modalities during surgery. This copying approach simplifies the real-time tracking system while maintaining high navigation precision.

Inventive Principle:
Principle #26Copying

Data Source

PatentUS20250371709A1Registering Intra-Operative Images Transformed from Pre-Operative Images of Different Imaging-Modality for Computer Assisted Navigation During Surgery
Publication Date: 2025.12.04 GLOBUS MEDICAL INC
  • US20250371709A1 patent drawing
  • US20250371709A1 patent drawing
  • US20250371709A1 patent drawing

AI summary

A computer platform is provided for computer assisted navigation during surgery. The computer platform includes at least one processor that is operative to transform pre-operative images of a patient obtained from a first imaging modality to an estimate of the pre-operative images of the patient in a second imaging modality that is different than the first imaging modality. The at least one processor is further operative to register the estimate of the pre-operative images of the patient in the second imaging modality to intra-operative navigable images or data of the patient.