Cryopreservation Bag Angled Drainage and Composite Structure
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Solution Overview
Problem
Current cryopreservation bags face issues with durability at freezing temperatures, leakage, and difficulty in drainage, which compromise the stability and handling of biologics during storage and transport.
Innovation Solution
The development of cryopreservation storage bags with a composite structure featuring a higher melting polymer inner surface and lower melting polymer outer surface, incorporating angled interfaces and drainage areas to enhance durability, flexibility, and drainage efficiency, while maintaining clarity and reducing leakage.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Strength
If the storage bag is reinforced to improve durability at freezing temperatures, then strength is improved, but visibility through the bag decreases and flexibility for manipulation decreases
Solution Approach 1:
The storage bag employs a composite structure consisting of an inner bag and an outer bag, where the inner bag provides durability and the outer bag maintains visibility and flexibility. This layered composite design allows each layer to fulfill its specific function without compromising the other properties.
2Strength
If the storage bag is reinforced to improve durability at freezing temperatures, then strength is improved, but flexibility for manipulation decreases
Solution Approach 1:
The storage bag employs a composite structure consisting of an inner bag and an outer bag, where the inner bag provides durability and the outer bag maintains visibility and flexibility. This layered composite design allows each layer to fulfill its specific function without compromising the other properties.
3Ease of operation
If the storage bag structure is simplified to improve drainage, then ease of operation is improved, but leakage control worsens
Solution Approach 1:
The storage bag features a nested structure with an inner bag positioned within an outer bag. The inner bag's angled bottom facilitates drainage, while the outer bag provides an additional containment layer with its own angled interface, creating a nested system that enhances both drainage efficiency and leakage prevention.
Solution Approach 2:
The inner and outer bags each have angled interfaces at their bottoms, creating localized drainage zones. This local quality enhancement at critical areas (the bottom interfaces) improves overall drainage efficiency without requiring complete structural redesign, maintaining reliability while enhancing operation.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The solution provides improved durability, reduced leakage, and enhanced drainage efficiency, ensuring the stability and effective handling of biologics at cryogenic temperatures, with increased flexibility and visibility.
Implementation Method 1
The first inner surface includes a first higher melting polymer and the first outer surface includes a first lower melting polymer
Implementation Method 2
at least a portion of the port tube not overlapping the main tube is sealed to itself such that at least a portion of the port tube, the main tube, or both the port tube and the main tube is shaped so as to form an angled drainage area
Data Source
AI summary
A storage bag (100) includes a main tube (102) extending from a first end to a second end and defining a first inner surface and outer surface. The main tube includes a first angled edge (128) and a second angled edge (132) extending from the first end of the main tube and forming a first angled interface. The storage bag also includes a port tube (104) extending from a first end to a second end and defining a second inner surface and outer surface. The second end of the port tube includes a third angled edge and a fourth angled edge extending from the second end of the port tube, forming a second angled interface. The second angled interface of the port tube is positioned over the first angled interface of the main tube. A portion of the port tube not overlapping the main tube is sealed to itself to form an angled drainage area (182).