Cryogenic Probe Vacuum Exhaust for Faster Cooling

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Solution Overview

Problem

Current cryosurgery systems, particularly liquid cryogenic systems, face challenges such as inefficient cooling due to phasing issues, high costs, and the need for single-use probes, as well as limited cooling capacity and long setup times.

Innovation Solution

The implementation of a cryogenic system that utilizes a vacuum source to draw liquid cryogen to the probe, eliminating the need for high-pressure gases and incorporating a dispersive medium within the probe to enhance cooling efficiency, along with a concentric insulating and exhaust conduit design to manage boil-off gas effectively.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Speed

If liquid nitrogen is pressurised to encourage faster cooling of the feed lines, then cooling speed is improved, but system complexity increases and phasing issues worsen

Engineering Contradiction:
Improvecooling speedVSAvoidsystem complexity
Core Design Contradiction:
SpeedVSDevice complexity

Solution Approach 1:

Instead of pressurizing the liquid nitrogen feed to accelerate cooling, the patent applies vacuum to the exhaust line to draw cryogen through the system. This inverted approach (using suction rather than pressure) achieves faster cooling without the complexity of pressure control systems and eliminates phasing issues by maintaining atmospheric or sub-atmospheric pressure throughout the feed line.

Inventive Principle:
Principle #13The other way round (Inversion)

Solution Approach 2:

The patent extracts the problematic pressurization step from the system and replaces it with vacuum application at the exhaust end. By removing the need for pressurized feed, the system eliminates the associated complexity and phasing problems while maintaining effective cooling performance.

Inventive Principle:
Principle #2Taking out (Extraction)

2Temperature

If Joule-Thompson devices are used to achieve low temperatures, then temperature is improved, but cooling capacity is limited

Engineering Contradiction:
ImprovetemperatureVSAvoidcooling capacity
Core Design Contradiction:
TemperatureVSProductivity

Solution Approach 1:

The patent utilizes the phase transition of liquid nitrogen to gas (evaporation) as the primary cooling mechanism. When liquid nitrogen evaporates, it absorbs latent heat of vaporization, providing vastly superior cooling capacity compared to the Joule-Thompson effect. This phase change process occurs naturally in the probe tip where the liquid nitrogen is delivered, creating effective cooling without requiring high-pressure gas expansion devices.

Inventive Principle:
Principle #36Phase transitions

3Temperature

If high pressure gas is used in Joule-Thompson devices, then cooling is achieved, but safety risks increase

Engineering Contradiction:
ImprovecoolingVSAvoidsafety risks
Core Design Contradiction:
TemperatureVSObject-affected harmful factors

Solution Approach 1:

The patent replaces the mechanical high-pressure gas expansion system with a vacuum-based liquid evaporation system. Instead of using high-pressure nitrogen oxide gas that requires containment and poses safety risks, the system uses atmospheric or vacuum conditions with liquid nitrogen that evaporates to provide cooling. This substitution eliminates the safety hazards associated with high-pressure gas while maintaining effective cooling performance.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

4Productivity

If liquid cryogenic systems are used to achieve superior heat absorption, then cooling capacity is improved, but setup time increases due to phasing

Engineering Contradiction:
Improveheat absorption capacityVSAvoidsetup time
Core Design Contradiction:
ProductivityVSLoss of time

Solution Approach 1:

The patent inverts the traditional approach by applying vacuum at the exhaust end rather than pressurizing the feed end. This causes the liquid nitrogen to be drawn through the system by suction, which accelerates the cooling of feed lines and eliminates phasing delays. The vacuum application creates a pressure gradient that promotes continuous, smooth flow of liquid nitrogen without the phasing problems that cause delays in traditional pressurized systems.

Inventive Principle:
Principle #13The other way round (Inversion)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This approach enables faster and more efficient cooling, reduces the need for multiple probes, allows for reusable components, and shortens treatment times, improving safety and reducing costs.

Implementation Method 1

a vacuum source configured such that it can suck or draw the liquid cryogen to the probe

Methodology Applied
Scientific EffectVacuum suction: Suction

Implementation Method 2

Liquid cryogenic devices rely on evaporation of a liquid, such as liquid nitrogen or helium, to produce cooling by boiling and/or evaporation

Methodology Applied
Scientific EffectEvaporation: Evaporation

Implementation Method 3

the cryogenic liquid boils and/or evaporates. When liquid nitrogen boils and/or evaporates the phase change results in an approximately 700 fold increase in volume

Methodology Applied
Scientific EffectBoiling: Boiling

Implementation Method 4

the latent heat of vaporisation for most cryogenic fluids commonly used in liquid cryogenic systems is significantly greater than the heat absorbed by the expanding gas(es) commonly used within Joule-Thompson systems

Methodology Applied
Scientific EffectLatent heat of vaporisation: Latent Heat

Implementation Method 5

a dispersive medium configured such that, in use, cryogen delivered to the probe disperses within the probe through the dispersive medium

Methodology Applied
Scientific EffectDispersion: Dispersion (of waves)

Implementation Method 6

concentric insulating and exhaust conduit design to manage boil-off gas effectively

Methodology Applied
Scientific EffectThermal insulation: Thermal Insulation

Data Source

PatentUS10363081B2Apparatus, probe and method for a cryogenic system
Publication Date: 2019.07.30 NITRO MEDICAL
  • US10363081B2 patent drawing
  • US10363081B2 patent drawing
  • US10363081B2 patent drawing

AI summary

An apparatus, probe and method for a cryogenic system are described. According to certain embodiments of the invention there is provided an apparatus for cryosurgery comprising: an exhaust line configured to receive cryogen from a probe; and a vacuum source configured to be in fluid communication with the exhaust line.