Cryopreservation Vial With Tear Line And Flanges
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Solution Overview
Problem
Cryopreservation vials face issues with sample contamination and damage due to leakage and thawing processes, where ice crystals can break cells and excessive heating stresses the sample, making it difficult to remove frozen samples without damaging them.
Innovation Solution
A vial design featuring a tubular body with a tear line and flanges that allows for the frozen sample to be ejected without thawing, by breaking the tear line to open the closed end, reducing contamination and damage risks.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Ease of operation
If the sample is thawed in a warm bath or heated block for removal, then the sample becomes easier to remove from the vial, but the sample becomes contaminated or damaged due to liquid immersion and excessive heating
Solution Approach 1:
The vial is pre-designed with a tear line and flanges that enable the closed end to be opened without thawing the sample. This preliminary structural preparation allows the sample to be removed in its frozen state, eliminating the need for harmful thawing procedures while maintaining ease of operation
Solution Approach 2:
The design extracts the sample from the vial in its frozen state by breaking the tear line and opening the closed end, removing the sample before any contamination or damage can occur during thawing processes
2Object-affected harmful factors
If the sample is removed in the frozen state without thawing, then sample contamination and damage are reduced, but it becomes difficult to remove the frozen sample due to adhesion to the vial wall surface
Solution Approach 1:
The vial structure is pre-configured with a tear line and flanges that, when activated, open the closed end to allow sample ejection. This preliminary design enables easy removal of the frozen sample by breaking the seal rather than overcoming adhesion through thawing
3Reliability
If the vial seal is maintained to prevent leakage, then sample integrity is preserved, but the sample becomes difficult to remove without thawing
Solution Approach 1:
The vial is segmented into a body and a closed end that can be separated by breaking the tear line. This segmentation allows the seal to be maintained during storage while enabling easy sample removal by separating the closed end from the body, preserving both integrity and operability
Solution Approach 2:
The tear line and flange structure are preliminarily designed to allow the closed end to be opened without compromising the seal during storage, enabling easy sample removal while maintaining sample integrity throughout the storage period
Data Source
AI summary
A vial is described herein that comprises a tubular body which comprises an opened end, a closed end, and a cavity, wherein the opened end is located at one end of the tubular body and the closed end is located at an opposing end of the tubular body. The tubular body further comprises a tear line located therein, wherein the tear line extends across at least a portion of one side of the tubular body, across the closed end, and across at least a portion of another side of the tubular body. In addition, the tubular body further comprises two flanges extending from the closed end, wherein the two flanges are configured to separate from one another outwardly from the tubular body and apply a force to break-open at least a portion of the tear line to open at least the closed end of the tubular body.