MRI-Guided Cryoablation System RF Heating Mitigation

Resolve Bottlenecks,
Find Innovative Solutions
Generate Solutions

Solution Overview

Problem

Cryosurgical systems face challenges in operating within MRI environments due to reactive effects such as RF heating and induced currents in metallic and electrical components, which can lead to component failure and corruption of fault detection circuits by high amplitude gradient and RF fields, making it difficult to determine if the MRI system is operational and mitigate these effects.

Innovation Solution

A magnetic resonance imaging (MRI) guided cryosurgical system that includes a control system capable of determining if the MRI system is operational and mitigating reactive effects by initiating cooling operations, disconnecting electrical components, and ignoring signals from temperature sensors and heaters when exposed to MR signals, using detectors to sense RF and magnetic fields and controlling the supply of cryofluid to counteract radiofrequency heating.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of operation

If surgical tools with metallic and electrical components are positioned in the MRI room for MRI-guided surgery, then imaging guidance is improved, but radiofrequency heating and induced currents cause harmful reactive effects on the surgical components

Engineering Contradiction:
ImproveMRI-guided surgical capabilityVSAvoidradiofrequency heating and induced currents
Core Design Contradiction:
Ease of operationVSObject-affected harmful factors

Solution Approach 1:

The control system proactively monitors MRI system operational status through detectors and preemptively mitigates reactive effects by initiating cooling operations and disconnecting electrical components before harmful heating and induced currents can occur, rather than reacting after damage occurs

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

A control system acts as an intermediary between the MRI system and surgical tools, using detectors to sense MRI operational status and automatically implementing mitigation strategies (cooling fluid delivery, electrical disconnection) to protect surgical components from harmful effects

Inventive Principle:
Principle #24Intermediary (Mediator)

2Measurement precision

If fault detection circuits are exposed to high amplitude gradient and RF fields during MRI operation, then MRI imaging is improved, but the fault detection circuits become corrupted and vulnerable to failure

Engineering Contradiction:
ImproveMRI imaging qualityVSAvoidfault detection circuit integrity
Core Design Contradiction:
Measurement precisionVSReliability

Solution Approach 1:

The control system detects MRI operational status in advance and preemptively disconnects electrical components and ignores fault detection signals during MRI operation, preventing circuit corruption before it occurs

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The system electrically disconnects vulnerable components (heaters, temperature sensors) from the circuit during MRI operation, removing them from the harmful electromagnetic environment to prevent signal corruption and circuit failure

Inventive Principle:
Principle #2Taking out (Extraction)

3Reliability

If the control system continuously monitors and mitigates reactive effects during MRI operation, then component safety is improved, but system complexity and operational overhead increase

Engineering Contradiction:
Improvecomponent safety during MRIVSAvoidcontrol system complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The control system automatically monitors MRI operational status through detectors and autonomously implements mitigation strategies (cooling fluid delivery, electrical disconnection, signal ignoring) without requiring manual intervention, making the complex safety management transparent to the user

Inventive Principle:
Principle #25Self-service

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The system effectively reduces reactive effects on cryosurgical components, allowing safe operation within MRI environments by cooling components, disconnecting electrical components, and managing signal processing to prevent corruption, thereby ensuring reliable operation and patient safety.

Implementation Method 1

a cryofluid can be delivered from a cryofluid source to one or more cryoprobes. The cryoprobe can be cooled as a result of expansion of the cryofluid, thereby freezing tissue in the vicinity of a tip of the cryoprobe.

Methodology Applied
Scientific EffectJoule-Thomson effect: Joule-Thomson Effect

Implementation Method 2

Some such systems include an electrical heater (in the form of a high resistance wire) positioned within the probe shaft of each cryoprobe to thaw tissue after freezing to facilitate removal of the cryoprobe.

Methodology Applied
Scientific EffectJoule heating: Joule Heating

Implementation Method 3

a magnetic resonance (MR) system positioned in an MR room configured to produce MR signals, such as magnetic fields and radiofrequency signals. The magnetic and radiofrequency fields permit imaging of a region of patient tissue.

Methodology Applied
Scientific EffectMagnetic resonance: Magnetic Field

Implementation Method 4

placement of surgical system having metallic and/or electrical components (e.g., probe shaft or heater wire and so on) adjacent to a MRI system may result in heating due to radiofrequency fields (radiofrequency heating), or induced current flow therethrough caused by the presence of the MRI magnet.

Methodology Applied
Scientific EffectElectromagnetic induction: Electromagnetic Induction

Data Source

PatentUS12042205B2Cryoablation system with magnetic resonance imaging detection
Publication Date: 2024.07.23 BIOCOMPATIBLES UK LTD
  • US12042205B2 patent drawing
  • US12042205B2 patent drawing
  • US12042205B2 patent drawing

AI summary

A magnetic resonance imaging (MRI) guided surgical system is provided that includes one or more surgical tools having components configured to develop reactive effects when exposed to MR signals generated by the MRI system. The system includes a control system that can determine whether the MR system is generating MR signals, and if the control system determines that the MR system is generating MR signals, mitigates the reactive effects of MR signals on components of the surgical tools. The system can include a cryoablation system with a cryoprobe having a probe shaft being made of a metallic material. If the control system determines that the MR system is generating MR signals, the control system can electrically disconnect the cryoprobe and/or ignore electrical signals generated by the electric heater in response to exposure to MR signals, and/or initiate a cooling operation of the probe shaft, whereby the cooling operation.