Cryoprobe Flow Restriction for Ablation Tip Temperature Control

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Solution Overview

Problem

Existing cryoprobes face challenges in regulating cryogen pressure at the ablation tip, leading to inconsistent temperature control and potential undesired cold exposure, and difficulty in accessing and ablating specific tissues effectively.

Innovation Solution

The cryoprobe design includes a malleable shaft with a fluid supply and exhaust conduit system, featuring a flow restricting element and insulating conduit, allowing for precise temperature regulation and targeted tissue ablation by varying the cross-sectional area of fluid flow and incorporating a flexible insulated conduit for thermal insulation.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Temperature

If the cryogen exhaust stream back pressure varies, then the temperature at the ablation tip varies substantially, but this leads to inconsistent temperature control

Engineering Contradiction:
Improvetemperature at ablation tipVSAvoidtemperature control consistency
Core Design Contradiction:
TemperatureVSReliability

Solution Approach 1:

The patent applies parameter changes by systematically varying the cross-sectional area of the exhaust conduit to regulate back pressure. The exhaust conduit includes a proximal section with a first cross-sectional area and a distal section with a second cross-sectional area that is smaller than the first, creating a flow restriction that stabilizes back pressure and consequently stabilizes the ablation tip temperature.

Inventive Principle:
Principle #35Parameter changes

2Temperature

If the ablation tip is cooled to extremely cold temperatures for effective ablation, then tissue ablation is achieved, but other portions of the cryoprobe may be exposed to undesired cold temperatures

Engineering Contradiction:
Improveablation tip temperatureVSAvoidundesired cold exposure
Core Design Contradiction:
TemperatureVSObject-affected harmful factors

Solution Approach 1:

The patent applies local quality by providing thermal insulation specifically at the distal end of the shaft where the ablation tip is located, while leaving other portions of the shaft uninsulated. The insulating conduit surrounds only the distal ablation section, allowing the tip to reach extremely cold temperatures for effective ablation while preventing heat loss from other portions of the probe that would cause undesired cold exposure.

Inventive Principle:
Principle #3Local quality

3Temperature

If the cross-sectional area of the exhaust conduit is reduced to increase back pressure, then temperature regulation improves, but the device complexity increases

Engineering Contradiction:
Improvetemperature regulation precisionVSAvoidconduit configuration complexity
Core Design Contradiction:
TemperatureVSDevice complexity

Solution Approach 1:

The patent applies segmentation by dividing the exhaust conduit into distinct sections with different cross-sectional areas. The exhaust conduit is segmented into a proximal section with a larger cross-sectional area and a distal section with a smaller cross-sectional area, allowing independent optimization of each section's function while maintaining overall system simplicity.

Inventive Principle:
Principle #1Segmentation

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This design enables precise temperature control at the ablation tip while maintaining other parts of the probe at warmer temperatures, facilitating effective tissue ablation and reducing unwanted cold exposure, and enhances the ability to engage and ablate tissues like intercostal nerves.

Implementation Method 1

a flow restricting element in fluid communication with the fluid exhaust conduit, the flow restricting element regulating the flow of fluid through at least a portion of the fluid exhaust conduit

Methodology Applied
Scientific EffectFlow restriction: Pressure Drop

Implementation Method 2

incorporating a flexible insulated conduit for thermal insulation

Methodology Applied
Scientific EffectThermal insulation: Thermal Insulation

Data Source

PatentEP3781060B1cryoprobe
Publication Date: 2025.11.05 ATRICURE INC
  • EP3781060B1 patent drawingFigure 1
  • EP3781060B1 patent drawingFigure 2
  • EP3781060B1 patent drawingFigure 3~4

AI summary

Cryosurgical devices, such as cryosurgical probes (cryoprobes) are disclosed. Some example embodiments may include an elongated shaft at least partially housing or delineating a fluid supply conduit and a fluid exhaust conduit, the elongated shaft including a distal ablation section terminating at a closed distal end, a housing at least partially circumscribing at least a portion of a proximal end of the elongated shaft and receiving or delineating at least a portion of the fluid supply conduit and a portion of the fluid exhaust conduit; and/or a flow restricting element in fluid communication with the fluid exhaust conduit, the flow restricting element regulating the flow of fluid through at least a portion of the fluid exhaust conduit.