Multi-Energy CT Denoising via Deep Learning Spectral-Spatial Processing

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Solution Overview

Problem

Multi-energy CT imaging faces challenges in noise reduction and artifact correction due to statistically correlated noise in material images, which can lead to undesirable texture artifacts and material misidentification.

Innovation Solution

A deep learning-based denoising framework that jointly denoises multiple basis material images in both spectral and spatial domains, using neural networks to transform and process input images, reducing correlated noise and artifacts while preserving image texture.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If multi-material decomposition is performed on multi-energy CT datasets, then material images representing multiple materials are obtained, but correlated noise is introduced that causes texture artifacts and material misidentification

Engineering Contradiction:
Improvematerial identification accuracyVSAvoidcorrelated noise and texture artifacts
Core Design Contradiction:
Measurement precisionVSObject-affected harmful factors

Solution Approach 1:

The patent segments the noise reduction problem into two distinct domains: spectral domain processing to address correlated noise between different material images, and spatial domain processing to address noise within each individual image. This segmentation allows each domain to be optimized independently with appropriate techniques for that specific type of noise correction.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent introduces a deep learning-based denoising network as an intermediary component between the multi-material decomposition process and the final material images. This neural network acts as a mediator that learns the complex noise patterns and artifacts introduced by decomposition and systematically removes them while preserving genuine material features.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Object-affected harmful factors

If conventional image denoising algorithms are applied to material images, then noise is reduced, but texture artifacts and material inaccuracy occur due to non-stationary correlated noise

Engineering Contradiction:
Improvenoise levelVSAvoidmaterial accuracy and texture fidelity
Core Design Contradiction:
Object-affected harmful factorsVSMeasurement precision

Solution Approach 1:

The patent extends the denoising approach from traditional single-image spatial domain processing to a multi-dimensional framework that simultaneously processes multiple material images across both spectral dimensions (different materials/energies) and spatial dimensions. This allows the system to exploit correlations across all dimensions to distinguish noise from genuine material features more effectively.

Inventive Principle:
Principle #17Another dimension (Dimensionality change)

Solution Approach 2:

The patent transforms the material images into a different parameter space using principal component analysis (PCA) or other linear transformations. In this transformed space, the correlated noise structure becomes more amenable to denoising operations, and the denoised images are then transformed back to the original material image space, preserving material accuracy while reducing noise.

Inventive Principle:
Principle #35Parameter changes

3Object-affected harmful factors

If deep learning-based denoising is applied in both spectral and spatial domains, then correlated noise and artifacts are reduced, but computational complexity increases

Engineering Contradiction:
Improvecorrelated noise and artifactsVSAvoidcomputational complexity
Core Design Contradiction:
Object-affected harmful factorsVSDevice complexity

Solution Approach 1:

The patent performs preliminary dimensionality reduction and noise characterization before applying the full deep learning denoising framework. By pre-processing the data to identify dominant noise patterns and reduce data dimensionality, the system prepares the input in a way that reduces the computational burden of the subsequent neural network processing while maintaining denoising effectiveness.

Inventive Principle:
Principle #10Preliminary action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The solution effectively reduces noise and artifacts in multi-energy CT images, producing clinically desirable, artifact-free material images and monochromatic representations with improved accuracy and texture preservation.

Implementation Method 1

jointly denoising the multiple basis material images in at least a spectral domain utilizing a deep learning-based denoising network

Methodology Applied
Scientific EffectDeep learning-based denoising:

Data Source

PatentUS11176642B2System and method for processing data acquired utilizing multi-energy computed tomography imaging
Publication Date: 2021.11.16 GE PRECISION HEALTHCARE LLC
  • US11176642B2 patent drawing
  • US11176642B2 patent drawing
  • US11176642B2 patent drawing

AI summary

A computer-implemented method for image processing is provided. The method includes acquiring multiple multi-energy spectral scan datasets and computing basis material images representative of multiple basis materials from the multi-energy spectral scan datasets, wherein the multiple basis material images include correlated noise. The method also includes jointly denoising the multiple basis material images in at least a spectral domain utilizing a deep learning-based denoising network to generate multiple de-noised basis material images.