CT Fluorescent X-Ray Detection for Contrast Agent Identification

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Solution Overview

Problem

Conventional X-ray CT apparatuses face challenges in achieving high independence of the observed energy spectrum due to detector response variations and interference from multiple substances within a living body, such as water and bones, which complicates the identification of target substances.

Innovation Solution

The X-ray CT apparatus incorporates a fluorescent X-ray detector to directly detect characteristic X-rays generated by a contrast agent, using a rotatable gantry with a rotary frame supporting an X-ray tube and detector, and a data acquisition system to process signals from both X-ray and fluorescent detectors, allowing for energy windowing to isolate target substance signals.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If conventional X-ray detectors are used to detect transmitted X-rays, then the detection system is simple, but the observed energy spectrum shows reduced independence due to detector response variations and interference from multiple substances

Engineering Contradiction:
Improveenergy spectrum independenceVSAvoiddetector system complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The detection system is segmented into two independent parts: a first X-ray detector for detecting transmitted X-rays and a second X-ray detector for detecting characteristic X-rays. This segmentation allows each detector to be optimized for its specific function, with the second detector specifically tuned to detect characteristic X-rays from the target substance, thereby improving energy spectrum independence without requiring the entire system to be complex

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The characteristic X-ray detection function is extracted from the transmitted X-ray detection function. By using a separate second X-ray detector specifically for detecting characteristic X-rays, the system isolates the target substance signal from the background interference caused by other substances, achieving improved measurement precision without making the overall device excessively complex

Inventive Principle:
Principle #2Taking out (Extraction)

2Measurement precision

If a single X-ray detector detects both transmitted X-rays and characteristic X-rays, then the device structure is simple, but the detection accuracy of target substances is reduced due to interference from water, bones, and other substances

Engineering Contradiction:
Improvetarget substance identification accuracyVSAvoiddetector configuration complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The detection function is segmented into two separate detectors: the first X-ray detector handles transmitted X-ray detection while the second X-ray detector handles characteristic X-ray detection. This segmentation enables the second detector to be optimized specifically for detecting characteristic X-rays from target substances, improving identification accuracy by eliminating interference from other substances like water and bones

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The second X-ray detector acts as an intermediary that specifically detects characteristic X-rays generated by the target substance. This intermediary detection path separates the target substance signal from the background signals produced by other substances, thereby improving measurement precision without requiring complex signal processing

Inventive Principle:
Principle #24Intermediary (Mediator)

3Measurement precision

If energy windowing is applied to isolate target substance signals, then the contrast-to-noise ratio is enhanced, but the data processing complexity increases

Engineering Contradiction:
Improvecontrast-to-noise ratioVSAvoidsignal processing complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

Energy windowing extracts the characteristic X-ray signals within a specific energy range from the total detected signals. By using the second X-ray detector that is specifically optimized for detecting characteristic X-rays, the system can apply energy windowing to isolate target substance signals, enhancing the contrast-to-noise ratio while keeping processing requirements manageable due to the specialized detector characteristics

Inventive Principle:
Principle #2Taking out (Extraction)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This approach enables highly independent detection of X-rays, improving the accuracy and contrast of marker substance identification by eliminating background interference, enhancing the contrast-to-noise ratio in generated images.

Implementation Method 1

an X-ray tube that generates an X-ray

Methodology Applied
Scientific EffectX-ray generation: X-Ray

Implementation Method 2

a fluorescent X-ray detector that detects a characteristic X-ray that is generated in accordance with a contrast agent

Methodology Applied
Scientific EffectFluorescence: Fluorescence

Data Source

PatentUS12465299B2X-ray CT apparatus
Publication Date: 2025.11.11 CANON MEDICAL SYST CORP
  • US12465299B2 patent drawing
  • US12465299B2 patent drawing
  • US12465299B2 patent drawing

AI summary

An X-ray CT apparatus of one embodiment includes an X-ray tube, a first X-ray detector, a rotator, and a second X-ray detector. The X-ray tube generates an X-ray. The first X-ray detector is arranged so as to face the X-ray tube and detects the X-ray that has transmitted through a subject. The rotator supports the X-ray tube and the first X-ray detector in a rotatable manner. The second X-ray detector detects a characteristic X-ray that is generated in accordance with a substance in the subject.