CT Image Display Material Decomposition for Bone Marrow Edema Detection

Resolve Bottlenecks,
Find Innovative Solutions
Generate Solutions

Solution Overview

Problem

Current CT image displays struggle to detect bone marrow edemas due to overlapping absorption changes from bone structures, making it difficult to diagnose bone marrow edemas and fractures using single or multispectra CT systems.

Innovation Solution

A method for preparing CT image displays by decomposing CT image data into at least three materials: bone mineral, yellow bone marrow, and red bone marrow, with normalization to remove bone mineral absorption components, allowing for the visualization of subtle absorption differences in bone marrow.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Device complexity

If material decomposition is performed into two materials (bone mineral and residual tissue), then the processing complexity is reduced, but the detection precision of bone marrow edemas deteriorates due to insufficient separation of bone marrow components

Engineering Contradiction:
Improvedecomposition complexityVSAvoidedema detection precision
Core Design Contradiction:
Device complexityVSMeasurement precision

Solution Approach 1:

The patent divides the bone marrow into two distinct components: red bone marrow and yellow bone marrow. This segmentation allows for separate analysis and normalization of each component, enabling the detection of subtle absorption changes in edematous bone marrow without being overwhelmed by the dominant bone mineral signal. The three-material decomposition model (bone mineral, red bone marrow, yellow bone marrow) provides the necessary granularity to isolate edema-related absorption changes.

Inventive Principle:
Principle #1Segmentation

2Measurement precision

If bone mineral absorption components are removed from pixel values, then the visibility of bone marrow edemas is improved, but the accuracy of bone mineral diagnosis deteriorates

Engineering Contradiction:
Improveedema visibilityVSAvoidbone mineral information
Core Design Contradiction:
Measurement precisionVSLoss of information

Solution Approach 1:

The patent applies different processing strategies to different regions of the image based on local characteristics. In regions dominated by bone mineral, the full three-material decomposition is performed to preserve bone mineral information for fracture diagnosis. In regions where bone marrow edema is suspected or present, the bone mineral component is normalized out or removed to enhance the visibility of subtle absorption changes in the bone marrow. This local adaptation of processing quality allows simultaneous optimization for both bone mineral and bone marrow diagnostics.

Inventive Principle:
Principle #3Local quality

3Measurement precision

If multienergy CT scanning is performed to enable material decomposition, then the detection capability for different materials is improved, but the examination time increases

Engineering Contradiction:
Improvematerial detection capabilityVSAvoidexamination time
Core Design Contradiction:
Measurement precisionVSLoss of time

Solution Approach 1:

The patent employs periodic switching between different X-ray energy spectra during the scanning process. The X-ray tube alternates between at least two different tube voltages (e.g., 80 kV and 140 kV) in a periodic manner, allowing the acquisition of multienergy data without requiring separate scanning sessions. This periodic action enables material decomposition and bone marrow edema detection within a single continuous examination, significantly reducing the total examination time compared to performing separate single-energy and MRI examinations.

Inventive Principle:
Principle #19Periodic action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This approach enhances the visibility of bone marrow edemas by reducing the dominance of bone mineral absorption, enabling the detection of small fluid incorporation changes and improving diagnostic accuracy in bone marrow conditions.

Implementation Method 1

compiling N≧2 CT image data records of an area of a patient on the basis of N different X-ray energy spectra

Methodology Applied
Scientific EffectX-ray generation: X-Ray

Implementation Method 2

carrying out material decomposition over at least one predetermined subarea of the area of the patient represented in the CT image data records with reference to at least three materials including at least bone mineral, yellow bone marrow and red bone marrow

Methodology Applied
Scientific EffectX-ray absorption: Absorption (EM radiation)

Data Source

PatentUS8542230B2Method for preparing CT image displays, and an arithmetic logic unit for carrying out this method
Publication Date: 2013.09.24 SIEMENS HEALTHINEERS AG
  • US8542230B2 patent drawing
  • US8542230B2 patent drawing
  • US8542230B2 patent drawing

AI summary

A method is disclosed for preparing CT image displays. In at least one embodiment, the method includes compiling N≧2 CT image data records of an area of a patient on the basis of N different X-ray energy spectra, each pixel or voxel being assigned an N-tuple CT numbers, each CT number of the N-tuple being assigned to the absorption value of one of the N X-ray energy spectra; carrying out material destruction over at least one predetermined subarea of the area of the patient represented in the CT image data records with reference to at least three materials including at least bone mineral, yellow bone marrow and red bone marrow; and outputting and/or displaying at least one CT image data record at least with reference to the predetermined subarea with absorption values relating to one of the N X-ray energy spectra or to a mathematically simulated spectrum from which the bone mineral content is extracted.